Well-ordered mesoporous silica nanoparticles as cell markers

Yu Shen Lin, Chih Pin Tsai, Hsing Yi Huang, Chieh Ti Kuo, Yann Hung, Dong Ming Huang, Yao Chang Chen, Chung Yuan Mou

研究成果: 雜誌貢獻文章同行評審

412 引文 斯高帕斯(Scopus)

摘要

Well-dispersed dye functionalized hexagonal crystal-like mesoporous silica nanoparticles were synthesized with high yield under dilute conditions, and the cell labeling capability was analyzed. The fluorescein isothiocyanate (FITC) functionalized mesoporous silica nanoparticles with sizes around 110 nm were demonstrated to be internalized into 3T3-L1 fibroblast cells and to accumulate in cytoplasm. The mesoporous silica nanoparticles appeared to have no apparent cytotoxic effects on the fibroblast cells. It was shown that the cellular internalization appears to be generic for various cells.

原文英語
頁(從 - 到)4570-4573
頁數4
期刊Chemistry of Materials
17
發行號18
DOIs
出版狀態已發佈 - 9月 6 2005
對外發佈

ASJC Scopus subject areas

  • 化學 (全部)
  • 化學工程 (全部)
  • 材料化學

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