Vitamin d deficiency is associated with severity of dry eye symptoms and primary sjögren’s syndrome: A systematic review and meta-analysis

Che Yuan Kuo, Yu Chen Huang, Ko Jo Lin, Tsung Yu Tsai

研究成果: 雜誌貢獻文章同行評審

1 引文 斯高帕斯(Scopus)

摘要

We aimed to examine the correlations between vitamin D deficiency, severity of dry eye symptoms and primary Sjögren’s syndrome (pSS) by performing a systematic review and meta-analysis. Online databases (PubMed, Cochrane Library, and Embase) were searched to identify controlled studies comparing (1) severity of dry eye symptoms between participants with and without vitamin D deficiency; and (2) serum vitamin D levels between patients with and without pSS. Eighteen studies were included. Overall, individuals with vitamin D deficiency had shorter tear breakup time (TBUT), lower Schirmer’s test scores and higher ocular surface disease index (OSDI) score than those without vitamin D deficiency. Additionally, serum vitamin D levels were found to be lower in pSS than controls. Our findings highlight the importance of vitamin D deficiency in the severity of dry eye symptoms and pSS.

原文英語
頁(從 - 到)386-388
頁數3
期刊Journal of Nutritional Science and Vitaminology
66
發行號4
DOIs
出版狀態已發佈 - 2020

ASJC Scopus subject areas

  • 醫藥(雜項)
  • 營養與營養學

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