Visfatin-a proinflammatory adipokine-in gallstone disease

Shen Nien Wang, Yao Tsung Yeh, Sen Teh Wang, Shih Chang Chuang, Chao Ling Wang, Ming Lung Yu, King Teh Lee

研究成果: 雜誌貢獻文章

13 引文 (Scopus)

摘要

Background: Visfatin is increasingly associated with several obesity-related diseases. The study is to evaluate if aberrant expression of circulating visfatin occurs in gallstone disease. Methods: An enzyme-linked immunosorbent assay was used to examine serum visfatin levels in 79 patients with cholesterol gallstones, 71 with pigment gallstones, and 223 healthy controls. The chemical composition of extracted gallstones was determined by Fourier transform infrared spectroscopy. Results: Serum visfatin levels were markedly elevated in the cholesterol and pigment gallstones in comparison with healthy controls. Furthermore, increased visfatin levels were associated with formation of the cholesterol and pigment gallstones. Intriguingly, a significant positive correlation between serum visfation levels and white cell count was noted in the cholesterol gallstones and controls. Moreover, the positive correlation in the cholesterol gallstones was more significant in the body mass index ≥25 subgroup than in the body mass index

原文英語
頁(從 - 到)459-465
頁數7
期刊American Journal of Surgery
199
發行號4
DOIs
出版狀態已發佈 - 四月 2010

指紋

Nicotinamide Phosphoribosyltransferase
Adipokines
Gallstones
Cholesterol
Body Mass Index
Serum
Fourier Transform Infrared Spectroscopy
Hypercholesterolemia
Obesity
Cell Count
Enzyme-Linked Immunosorbent Assay

ASJC Scopus subject areas

  • Surgery

引用此文

Wang, S. N., Yeh, Y. T., Wang, S. T., Chuang, S. C., Wang, C. L., Yu, M. L., & Lee, K. T. (2010). Visfatin-a proinflammatory adipokine-in gallstone disease. American Journal of Surgery, 199(4), 459-465. https://doi.org/10.1016/j.amjsurg.2009.01.014

Visfatin-a proinflammatory adipokine-in gallstone disease. / Wang, Shen Nien; Yeh, Yao Tsung; Wang, Sen Teh; Chuang, Shih Chang; Wang, Chao Ling; Yu, Ming Lung; Lee, King Teh.

於: American Journal of Surgery, 卷 199, 編號 4, 04.2010, p. 459-465.

研究成果: 雜誌貢獻文章

Wang, SN, Yeh, YT, Wang, ST, Chuang, SC, Wang, CL, Yu, ML & Lee, KT 2010, 'Visfatin-a proinflammatory adipokine-in gallstone disease', American Journal of Surgery, 卷 199, 編號 4, 頁 459-465. https://doi.org/10.1016/j.amjsurg.2009.01.014
Wang, Shen Nien ; Yeh, Yao Tsung ; Wang, Sen Teh ; Chuang, Shih Chang ; Wang, Chao Ling ; Yu, Ming Lung ; Lee, King Teh. / Visfatin-a proinflammatory adipokine-in gallstone disease. 於: American Journal of Surgery. 2010 ; 卷 199, 編號 4. 頁 459-465.
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abstract = "Background: Visfatin is increasingly associated with several obesity-related diseases. The study is to evaluate if aberrant expression of circulating visfatin occurs in gallstone disease. Methods: An enzyme-linked immunosorbent assay was used to examine serum visfatin levels in 79 patients with cholesterol gallstones, 71 with pigment gallstones, and 223 healthy controls. The chemical composition of extracted gallstones was determined by Fourier transform infrared spectroscopy. Results: Serum visfatin levels were markedly elevated in the cholesterol and pigment gallstones in comparison with healthy controls. Furthermore, increased visfatin levels were associated with formation of the cholesterol and pigment gallstones. Intriguingly, a significant positive correlation between serum visfation levels and white cell count was noted in the cholesterol gallstones and controls. Moreover, the positive correlation in the cholesterol gallstones was more significant in the body mass index ≥25 subgroup than in the body mass index",
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AU - Yeh, Yao Tsung

AU - Wang, Sen Teh

AU - Chuang, Shih Chang

AU - Wang, Chao Ling

AU - Yu, Ming Lung

AU - Lee, King Teh

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KW - Pigment

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