Ventricular geometric characteristics and functional benefit of mild right ventricular outflow tract obstruction in patients with significant pulmonary regurgitation after repair of tetralogy of Fallot

Chun An Chen; Ssu Yuan Chen; Jou Kou Wang; Wen Yih Isaac Tseng; Hsin Hui Chiu; Chung I. Chang; Ing Sh Chiu; Yih Sharng Chen; Ming Chun Yang; Chun Wei Lu; Ming Tai Lin; Mei Hwan Wu

doi:10.1016/j.ahj.2013.12.026

Ventricular geometric characteristics and functional benefit of mild right ventricular outflow tract obstruction in patients with significant pulmonary regurgitation after repair of tetralogy of Fallot

Chun An Chen, Ssu Yuan Chen, Jou Kou Wang, Wen Yih Isaac Tseng, Hsin Hui Chiu, Chung I. Chang, Ing Sh Chiu, Yih Sharng Chen, Ming Chun Yang, Chun Wei Lu, Ming Tai Lin, Mei Hwan Wu

研究成果: 雜誌貢獻 › 文章 › 同行評審

16 引文斯高帕斯（Scopus）

摘要

Background Right ventricular (RV) outflow tract obstruction (RVOTO) might protect the RV from adverse remodeling caused by significant pulmonary regurgitation (PR) in patients with repaired tetralogy of Fallot (rTOF), but the underlying mechanisms and influences on exercise tolerance remain unclear. This study sought to investigate the impacts from mild RVOTO on ventricular remodeling and exercise capacity in rTOF. Methods Eighty-five rTOF patients with a PR fraction ≥20% were assessed with cardiac magnetic resonance, cardiopulmonary exercise test, and echocardiography. Patients with a peak RVOT pressure gradient 20-50 mmHg were considered to have mild RVOTO (n = 29), while those with a gradient

原文	英語
頁（從 - 到）	555-561
頁數	7
期刊	American Heart Journal
卷	167
發行號	4
DOIs	https://doi.org/10.1016/j.ahj.2013.12.026
出版狀態	已發佈 - 4月 2014

ASJC Scopus subject areas

心臟病學與心血管醫學

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10.1016/j.ahj.2013.12.026

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Chen, C. A., Chen, S. Y., Wang, J. K., Tseng, W. Y. I., Chiu, H. H., Chang, C. I., Chiu, I. S., Chen, Y. S., Yang, M. C., Lu, C. W., Lin, M. T., & Wu, M. H. (2014). Ventricular geometric characteristics and functional benefit of mild right ventricular outflow tract obstruction in patients with significant pulmonary regurgitation after repair of tetralogy of Fallot. American Heart Journal, 167(4), 555-561. https://doi.org/10.1016/j.ahj.2013.12.026

Ventricular geometric characteristics and functional benefit of mild right ventricular outflow tract obstruction in patients with significant pulmonary regurgitation after repair of tetralogy of Fallot. / Chen, Chun An; Chen, Ssu Yuan; Wang, Jou Kou 等.

於: American Heart Journal, 卷 167, 編號 4, 04.2014, p. 555-561.

研究成果: 雜誌貢獻 › 文章 › 同行評審

Chen, CA, Chen, SY, Wang, JK, Tseng, WYI, Chiu, HH, Chang, CI, Chiu, IS, Chen, YS, Yang, MC, Lu, CW, Lin, MT & Wu, MH 2014, 'Ventricular geometric characteristics and functional benefit of mild right ventricular outflow tract obstruction in patients with significant pulmonary regurgitation after repair of tetralogy of Fallot', American Heart Journal, 卷 167, 編號 4, 頁 555-561. https://doi.org/10.1016/j.ahj.2013.12.026

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abstract = "Background Right ventricular (RV) outflow tract obstruction (RVOTO) might protect the RV from adverse remodeling caused by significant pulmonary regurgitation (PR) in patients with repaired tetralogy of Fallot (rTOF), but the underlying mechanisms and influences on exercise tolerance remain unclear. This study sought to investigate the impacts from mild RVOTO on ventricular remodeling and exercise capacity in rTOF. Methods Eighty-five rTOF patients with a PR fraction ≥20% were assessed with cardiac magnetic resonance, cardiopulmonary exercise test, and echocardiography. Patients with a peak RVOT pressure gradient 20-50 mmHg were considered to have mild RVOTO (n = 29), while those with a gradient ",

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AU - Chen, Chun An

AU - Chen, Ssu Yuan

AU - Wang, Jou Kou

AU - Tseng, Wen Yih Isaac

AU - Chiu, Hsin Hui

AU - Chang, Chung I.

AU - Chiu, Ing Sh

AU - Chen, Yih Sharng

AU - Yang, Ming Chun

AU - Lu, Chun Wei

AU - Lin, Ming Tai

AU - Wu, Mei Hwan

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AB - Background Right ventricular (RV) outflow tract obstruction (RVOTO) might protect the RV from adverse remodeling caused by significant pulmonary regurgitation (PR) in patients with repaired tetralogy of Fallot (rTOF), but the underlying mechanisms and influences on exercise tolerance remain unclear. This study sought to investigate the impacts from mild RVOTO on ventricular remodeling and exercise capacity in rTOF. Methods Eighty-five rTOF patients with a PR fraction ≥20% were assessed with cardiac magnetic resonance, cardiopulmonary exercise test, and echocardiography. Patients with a peak RVOT pressure gradient 20-50 mmHg were considered to have mild RVOTO (n = 29), while those with a gradient

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Ventricular geometric characteristics and functional benefit of mild right ventricular outflow tract obstruction in patients with significant pulmonary regurgitation after repair of tetralogy of Fallot

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