Vacuolating megalencephalic leukoencephalopathy with mild clinical course validated by diffusion tensor imaging and MR spectroscopy

Yi Fang Tu, Cheng Yu Chen, Chao Ching Huang, Chang Shin Lee

研究成果: 雜誌貢獻文章同行評審

9 引文 斯高帕斯(Scopus)

摘要

We report a case of presumed vacuolating megalencephalic leukoencephalopathy (VML) in a 5-year-old boy that was diagnosed when the patient was 34 months old. The patient presented clinically with megalencephaly and delayed onset of slowly progressive neurologic dysfunction. Serial MR imaging and biochemical analysis were performed to differentiate VML from other disease entities with megalencephaly and leukoencephalopathy of infantile onset. Information obtained with diffusion tensor MR imaging revealed nearly intact white matter anisotropy and vectors in parietal and posterior temporal lobes in which hyperintense abnormality was shown on conventional T2-weighted images, and proton MR spectra showed a significant decrease in N-acetylaspartate-creatine + phosphocreatine ratio.
原文英語
頁(從 - 到)1041-1045
頁數5
期刊American Journal of Neuroradiology
25
發行號6
出版狀態已發佈 - 六月 2004
對外發佈

ASJC Scopus subject areas

  • 神經病學(臨床)
  • 放射學、核子醫學和影像學
  • 放射與超音波技術

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