Using NF-κB as a molecular target for theranostics in radiation oncology research

Yu Chang Liu, I. Tsang Chiang, Fei Ting Hsu, Jeng Jong Hwang

研究成果: 雜誌貢獻回顧型文獻

24 引文 (Scopus)

摘要

Resistance of cancer cells to chemotherapy and/or radiotherapy is a major challenge to current anticancer treatment. The NF-κB signaling pathway plays an important role in tumor development and progression, and results in unsatisfactory treatment outcome. Inhibition of the NF-κB signaling cascade may sensitize the resistant cancer cells to chemotherapy and/or radiotherapy. Here, the correlation of NF-κB molecules with carcinogenesis and tumor progression, along with its significance in clinical practice, is reviewed. The potential clinical application of NF-κB and its associated molecules as diagnostic and therapeutic targets is also discussed.
原文英語
頁(從 - 到)139-146
頁數8
期刊Expert Review of Molecular Diagnostics
12
發行號2
DOIs
出版狀態已發佈 - 三月 2012
對外發佈Yes

指紋

Radiation Oncology
Research
Neoplasms
Radiotherapy
Drug Therapy
Carcinogenesis
Theranostic Nanomedicine
Therapeutics

ASJC Scopus subject areas

  • Molecular Medicine
  • Molecular Biology
  • Genetics
  • Pathology and Forensic Medicine

引用此文

Using NF-κB as a molecular target for theranostics in radiation oncology research. / Liu, Yu Chang; Chiang, I. Tsang; Hsu, Fei Ting; Hwang, Jeng Jong.

於: Expert Review of Molecular Diagnostics, 卷 12, 編號 2, 03.2012, p. 139-146.

研究成果: 雜誌貢獻回顧型文獻

Liu, Yu Chang ; Chiang, I. Tsang ; Hsu, Fei Ting ; Hwang, Jeng Jong. / Using NF-κB as a molecular target for theranostics in radiation oncology research. 於: Expert Review of Molecular Diagnostics. 2012 ; 卷 12, 編號 2. 頁 139-146.
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