Using cortical function mapping by awake craniotomy dealing with the patient with recurrent glioma in the eloquent cortex

Ying-Ching Li, Hsiao-Yean Chiu, Kuo-Chen Wei, Ya-Jui Lin, Ko-Ting Chen, Peng-Wei Hsu, Yin-Cheng Huang, Pin-Yuan Chen

研究成果: 雜誌貢獻文章同行評審


Background Awake craniotomy is an effective method by which to reduce postoperative neurologic deficit in newly-diagnosed glioma patients. However, the level of functional preservation in patients undergoing resection of recurrent glioma remains unknown. Therefore, this study aimed to evaluate functional outcomes in patients with recurrent glioma undergoing awake craniotomy as compared with conservative general anesthesia craniotomy for tumor resection. Material and methods We retrospectively reviewed 225 patients who had recurrent gliomas from May 2013 to January 2016 in our institution. New-onset neurological deficits were evaluated on postoperative day 7 (early) and at 3 months (late). General performance was assessed both preoperatively and at 3 months postoperatively. Results The early neurological deficit rate was 3.8% in the awake craniotomy group and 21.6% in the general anesthesia group (P = 0.032), while the late neurological deficit rates were 3.8% and 11.5%, respectively (P = 0.231). Moreover, 46.1% of patients in the awake craniotomy group and 12.6% in the general anesthesia group demonstrated an improvement in the Karnofsky performance status (KPS) score (P 
期刊Biomedical Journal
出版狀態打印前電子出版 - 六月 2020


  • Awake craniotomy
  • General anesthesia
  • Glioma
  • KPS
  • Glioblastoma
  • Neurologic deficits