Usefulness of Pulmonary Arterial Flow Discordance to Identify Pulmonary Embolism

Shih Hung Hsiao, Chiu Yen Lee, Shu Mei Chang, Shu Hsin Yang, Shih Kai Lin, Kuan Rau Chiou

研究成果: 雜誌貢獻文章

1 引文 (Scopus)

摘要

The present study was undertaken to determine the sensitivity and specificity of echocardiography in the diagnosis of pulmonary embolism (PE). The study consisted of 2 stages. First, 600 patients were enrolled to measure bilateral pulmonary blood flow by echocardiography. Using multidetector row computed tomography, 200 subjects were diagnosed with pulmonary hypertension and 100 with defined PE. Another 300 subjects without cardiopulmonary distress served as controls. The time-velocity integral (TVI) and flow volume of both pulmonary arteries were obtained. The percentage differences in bilateral pulmonary arterial TVI (ΔTVI/mean) were 12.0 ± 9.3%, 13.8 ± 12.1%, and 38.6 ± 14.9% for controls, subjects with pulmonary hypertension, and subjects with PE, respectively. The percentage differences in bilateral pulmonary flow (Δflow/mean) were 15.1 ± 11.7%, 17.6 ± 14.9%, and 36.8 ± 17.5% for controls, subjects with pulmonary hypertension, and subjects with PE, respectively. By receiver-operating characteristic curve analysis, the cut-off points for ΔTVI/mean and Δflow/mean to identify PE were 25% and 26.5%, respectively. In the second part of study, the accuracy of ΔTVI/mean and Δflow/mean to screen 300 patients with suspected PE was tested. Echocardiography provided high degrees of sensitivity and specificity for the diagnosis of PE. In conclusion, bilateral pulmonary arterial flow measurement is a simple and useful test to assess the possibility of PE.
原文英語
頁(從 - 到)579-583
頁數5
期刊American Journal of Cardiology
99
發行號4
DOIs
出版狀態已發佈 - 二月 15 2007
對外發佈Yes

指紋

Pulmonary Embolism
Lung
Pulmonary Hypertension
Echocardiography
Sensitivity and Specificity
Multidetector Computed Tomography
ROC Curve
Pulmonary Artery

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

引用此文

Usefulness of Pulmonary Arterial Flow Discordance to Identify Pulmonary Embolism. / Hsiao, Shih Hung; Lee, Chiu Yen; Chang, Shu Mei; Yang, Shu Hsin; Lin, Shih Kai; Chiou, Kuan Rau.

於: American Journal of Cardiology, 卷 99, 編號 4, 15.02.2007, p. 579-583.

研究成果: 雜誌貢獻文章

Hsiao, Shih Hung ; Lee, Chiu Yen ; Chang, Shu Mei ; Yang, Shu Hsin ; Lin, Shih Kai ; Chiou, Kuan Rau. / Usefulness of Pulmonary Arterial Flow Discordance to Identify Pulmonary Embolism. 於: American Journal of Cardiology. 2007 ; 卷 99, 編號 4. 頁 579-583.
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abstract = "The present study was undertaken to determine the sensitivity and specificity of echocardiography in the diagnosis of pulmonary embolism (PE). The study consisted of 2 stages. First, 600 patients were enrolled to measure bilateral pulmonary blood flow by echocardiography. Using multidetector row computed tomography, 200 subjects were diagnosed with pulmonary hypertension and 100 with defined PE. Another 300 subjects without cardiopulmonary distress served as controls. The time-velocity integral (TVI) and flow volume of both pulmonary arteries were obtained. The percentage differences in bilateral pulmonary arterial TVI (ΔTVI/mean) were 12.0 ± 9.3{\%}, 13.8 ± 12.1{\%}, and 38.6 ± 14.9{\%} for controls, subjects with pulmonary hypertension, and subjects with PE, respectively. The percentage differences in bilateral pulmonary flow (Δflow/mean) were 15.1 ± 11.7{\%}, 17.6 ± 14.9{\%}, and 36.8 ± 17.5{\%} for controls, subjects with pulmonary hypertension, and subjects with PE, respectively. By receiver-operating characteristic curve analysis, the cut-off points for ΔTVI/mean and Δflow/mean to identify PE were 25{\%} and 26.5{\%}, respectively. In the second part of study, the accuracy of ΔTVI/mean and Δflow/mean to screen 300 patients with suspected PE was tested. Echocardiography provided high degrees of sensitivity and specificity for the diagnosis of PE. In conclusion, bilateral pulmonary arterial flow measurement is a simple and useful test to assess the possibility of PE.",
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