摘要
Background: The white blood cell (WBC) count was one of the first inflammatory markers associated with metabolic syndrome (MetS). Recently, two longitudinal studies have demonstrated a cause and effect relationship between MetS and WBC counts among middle-aged adults. However, no study has used WBC cutoff values to predict MetS in the elderly.
Methods: Subjects who underwent routine health checkups, and were above 60 years of age, were enrolled. All subjects were followed-up until they developed MetS or until 4 years from the date of entry, whichever came earlier. Of the 4539 subjects eligible for enrollment, 3428 subjects comprised the study group and 1111 subjects comprised the validation group.
Results: WBC counts were significantly different between subjects with and without MetS in both genders. Using the ROC curve, WBC cutoff values of 5.7 × 103/l in males and 5.0 × 103/l in females were associated with the increased risk of developing MetS (all p values
Conclusions: The association between WBC count and MetS was gender specific. A WBC cutoff value greater than 5.0 103/l may predict the development of MetS in elderly women.
| 原文 | 英語 |
|---|---|
| 頁（從 - 到） | 230-237 |
| 頁數 | 8 |
| 期刊 | Aging Male |
| 卷 | 17 |
| 發行號 | 4 |
| DOIs | |
| 出版狀態 | 已發佈 - 十二月 1 2014 |
指紋
ASJC Scopus subject areas
- Geriatrics and Gerontology
- Medicine(all)
引用此文
Use of white blood cell counts to predict metabolic syndrome in the elderly : A 4 year longitudinal study. / Chao, Ting Ting; Hsieh, Chang Hsun; Lin, Jiunn Diann; Wu, Chung Ze; Hsu, Chun Hsien; Pei, Dee; Chen, Yen Lin; Liang, Yao Jen; Chang, Jin Biou.
於: Aging Male, 卷 17, 編號 4, 01.12.2014, p. 230-237.研究成果: 雜誌貢獻 › 文章
}
TY - JOUR
T1 - Use of white blood cell counts to predict metabolic syndrome in the elderly
T2 - A 4 year longitudinal study
AU - Chao, Ting Ting
AU - Hsieh, Chang Hsun
AU - Lin, Jiunn Diann
AU - Wu, Chung Ze
AU - Hsu, Chun Hsien
AU - Pei, Dee
AU - Chen, Yen Lin
AU - Liang, Yao Jen
AU - Chang, Jin Biou
PY - 2014/12/1
Y1 - 2014/12/1
N2 - Background: The white blood cell (WBC) count was one of the first inflammatory markers associated with metabolic syndrome (MetS). Recently, two longitudinal studies have demonstrated a cause and effect relationship between MetS and WBC counts among middle-aged adults. However, no study has used WBC cutoff values to predict MetS in the elderly.Methods: Subjects who underwent routine health checkups, and were above 60 years of age, were enrolled. All subjects were followed-up until they developed MetS or until 4 years from the date of entry, whichever came earlier. Of the 4539 subjects eligible for enrollment, 3428 subjects comprised the study group and 1111 subjects comprised the validation group.Results: WBC counts were significantly different between subjects with and without MetS in both genders. Using the ROC curve, WBC cutoff values of 5.7 × 103/l in males and 5.0 × 103/l in females were associated with the increased risk of developing MetS (all p values Conclusions: The association between WBC count and MetS was gender specific. A WBC cutoff value greater than 5.0 103/l may predict the development of MetS in elderly women.
AB - Background: The white blood cell (WBC) count was one of the first inflammatory markers associated with metabolic syndrome (MetS). Recently, two longitudinal studies have demonstrated a cause and effect relationship between MetS and WBC counts among middle-aged adults. However, no study has used WBC cutoff values to predict MetS in the elderly.Methods: Subjects who underwent routine health checkups, and were above 60 years of age, were enrolled. All subjects were followed-up until they developed MetS or until 4 years from the date of entry, whichever came earlier. Of the 4539 subjects eligible for enrollment, 3428 subjects comprised the study group and 1111 subjects comprised the validation group.Results: WBC counts were significantly different between subjects with and without MetS in both genders. Using the ROC curve, WBC cutoff values of 5.7 × 103/l in males and 5.0 × 103/l in females were associated with the increased risk of developing MetS (all p values Conclusions: The association between WBC count and MetS was gender specific. A WBC cutoff value greater than 5.0 103/l may predict the development of MetS in elderly women.
KW - Elderly
KW - Longitudinal
KW - Metabolic syndrome
KW - Prediction
KW - WBC
UR - http://www.scopus.com/inward/record.url?scp=84911937358&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84911937358&partnerID=8YFLogxK
U2 - 10.3109/13685538.2013.875989
DO - 10.3109/13685538.2013.875989
M3 - Article
C2 - 24456526
AN - SCOPUS:84911937358
VL - 17
SP - 230
EP - 237
JO - Aging Male
JF - Aging Male
SN - 1368-5538
IS - 4
ER -