Urothelial carcinoma of the urinary bladder in young adults - Clinical experience at Taipei Veterans General Hospital

Yu Ching Wen, Junne Yih Kuo, Kuang Kuo Chen, Alex T L Lin, Yen Hwa Chang, Yen Shen Hsu, Luke S. Chang

研究成果: 雜誌貢獻文章同行評審

19 引文 斯高帕斯(Scopus)

摘要

Background: The clinical behavior and prognosis of bladder cancer in young patients is not well defined. The aim of this study was, therefore, to evaluate the clinical behavior, pathologic characteristics and prognosis of urothelial carcinoma of the urinary bladder in young adults. Methods: We retrospectively reviewed records from 30 young patients (23 males, 7 females; age ≤ 40 years) with urothelial carcinoma of the urinary bladder who had been treated in our hospital between May 1990 and October 2003. Data were analyzed by the Kaplan-Meier method to assess disease recurrence and survival. Results: The mean age at diagnosis was 34.3 ± 5 years (range, 22-40 years). Fifteen patients presented with pTa, 9 with pT1, 4 with pT2, 1 with pT3, and 1 with pT4. Twenty-six patients (87.2%) had low-grade bladder cancer, and the other 4 had high-grade disease. The most frequent initial presenting symptom was gross hematuria. The mean postoperative follow-up period was 72.8 months (range, 4-149 months). Fifty percent of superficial bladder cancers recurred a mean of 10.7 months (range, 3-68 months) after operation. One patient died from invasive bladder cancer after radical cystectomy, and 1 died from superficial bladder cancer due to tumor progression. The 5-year cancer-specific survival rate was 95.2% for superficial cancer and 83.3% for invasive cancer. The overall survival rate was 93.3%. Conclusion: Urothelial carcinoma of the urinary bladder in young adults is usually associated with low grade and low stage. Invasive bladder cancer had no worse a survival rate than superficial bladder cancer.
原文英語
頁(從 - 到)272-275
頁數4
期刊Journal of the Chinese Medical Association
68
發行號6
出版狀態已發佈 - 六月 2005
對外發佈Yes

ASJC Scopus subject areas

  • Medicine(all)

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