Uremic toxins-novel arrhythmogenic factor in chronic kidney disease-related atrial fibrillation

Shih Yu Huang, Yi Ann Chen, Shih Ann Chen, Yi Jen Chen, Yung Kuo Lin

研究成果: 雜誌貢獻文章

6 引文 斯高帕斯(Scopus)

摘要

Atrial fibrillation (AF) is the most common cardiac arrhythmia. Chronic kidney disease (CKD) is associated with a high prevalence of AF, and uremic toxins are an important risk factor for cardiovascular diseases associated with CKD. Uremic toxins can produce pro-fibrotic, pro-hypertrophic, and pro-inflammatory effects on cardiac tissues and enhance oxidative stress or neurohormonal phenomena of cardiovascular injury, which are recognized as arrhythmogenic factors of AF. This article reviews the clinical, molecular, and electrophysiological data of uremic toxins in CKD considered to induce AF through multiple mechanisms on structural and electrical remodeling of the cardiovascular system.

原文英語
頁(從 - 到)259-264
頁數6
期刊Acta Cardiologica Sinica
32
發行號3
DOIs
出版狀態已發佈 - 五月 1 2016

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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