Urban air pollution increases plasma fibrinogen and plasminogen activator inhibitor-1 levels in susceptible patients

Ta Chen Su, Chang Chuan Chan, Chiau Suong Liau, Lian Yu Lin, Hsian Li Kao, Kai Jen Chuang

研究成果: 雜誌貢獻文章同行評審

20 引文 斯高帕斯(Scopus)

摘要

BACKGROUND: The cardiovascular effects on fibrinolytic activity by urban air pollution are still unknown. METHODS: Paired fasting blood samples during high and low air pollution days in Taipei were taken from a panel of 49 patients with coronary heart disease or multiple risk factors to study their fibrinolytic and inflammatory response to urban air pollution. Paired t-tests and mixed-effects models were used to determine the air pollution effects. RESULTS: Patients' plasma plasminogen activator inhibitor-1 levels were significantly increased when hourly concentrations of particulate matter with diameters less than 10 μm (PM10) were greater than 100 μg/m during the period 0800 to 1800 h. CONCLUSION: Urban air pollution has an adverse effect on plasma fibrinolytic function in a susceptible population.

原文英語
頁(從 - 到)849-852
頁數4
期刊European Journal of Cardiovascular Prevention and Rehabilitation
13
發行號5
DOIs
出版狀態已發佈 - 十月 2006
對外發佈

ASJC Scopus subject areas

  • 心臟病學與心血管醫學
  • 復健
  • 公共衛生、環境和職業健康

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