摘要
Several unusual cytogenetic changes have occurred during the evolution of chronic myelogenous leukemia in a 32 year old white male with this disease for 8 years. The first appearance of a hypodiploid cell line containing a dicentric marker occurred 2 years after diagnosis and this line was eliminated by several courses of therapy with hydroxyurea. A second clone, which had a partial deletion of the long arm of one of the number 8 chromosomes (8q-) was noted a year later, but this line is refractory to intensive combination chemotherapy.
原文 | 英語 |
---|---|
頁(從 - 到) | 345-354 |
頁數 | 10 |
期刊 | Acta Haematologica |
卷 | 56 |
發行號 | 6 |
出版狀態 | 已發佈 - 12月 1 1976 |
對外發佈 | 是 |
ASJC Scopus subject areas
- 醫藥 (全部)
- 血液學