Unreliability of pulse contour-derived cardiac output in piglets simulating acute hemorrhagic shock and rapid volume expansion

Chih Hsin Lee, Jann Yuan Wang, Kuo Liang Huang, Hung Wen Chiu, Tsung Ching Fei, Tsui Shia Chen, Hung Chang

研究成果: 雜誌貢獻文章同行評審

9 引文 斯高帕斯(Scopus)

摘要

Background: Pulse contour-derived cardiac output for continuous hemodynamic monitoring is becoming popular in critical care. However, the data regarding its reliability during acute hemodynamic instability are inconsistent. This study was conducted to determine whether pulse contour-derived cardiac output truly reflects rapid hemodynamic changes. Methods: Hemorrhagic shock was created in seven anesthetized piglets by continuous blood withdrawal at a rate of 1 mL • kg • min for 20 minutes. Volume expansion with 10% hydroxyethyl starch 8 mL • kg was then administered for 5 minutes. Pulse contour-derived and thermodilution- derived hemodynamic parameters were compared. Results: Baseline thermodilution-derived cardiac index was 3.2 ± 0.4 L • min • M. After exsanguination, it decreased to 2.1 ± 0.3 L • min • M while pulse contour-derived cardiac index increased to 4.4 ± 0.4 L • min • M (p value
原文英語
頁(從 - 到)1357-1361
頁數5
期刊Journal of Trauma - Injury, Infection and Critical Care
68
發行號6
DOIs
出版狀態已發佈 - 六月 2010
對外發佈Yes

ASJC Scopus subject areas

  • Surgery
  • Critical Care and Intensive Care Medicine

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