Typhlitis as the initial presentation of acute lymphocytic leukemia - A case report

Ming Cheh Chen, Hans Hsienhong Lin, Chih Hsun Yi, Chien Lin Chen, Lu Chin Huang, Ruey Ho Kao

研究成果: 雜誌貢獻文章

1 引文 (Scopus)

摘要

We report a case of typhlitis as the initial presentation of adult acute lymphocytic leukemia (ALL). A forty-five year old man presented with fever, right lower quadrant pain and diarrhea. On admission the hemogram revealed 67% blast cells in the peripheral blood. A cytochemical study confirmed a diagnosis of ALL. The absolute neutrophil count dropped to 117 three days later. Abdominal computerized tomography showed that the colon was swollen on the right side with an abnormally thickened wall and infiltrations in the pericolic fat. Stool analysis was positive for occult blood and Giardia lamblia. Typhlitis complicating ALL was considered and empirical antibiotics (ceftazidime and metronidazole) which covered Gram negative bacilli, anaerobic bacteria and Giardia lamblia were instituted. The typhilitis symptoms improved and a follow-up abdominal MRI study showed complete resolution of right side colon disease. Standard chemotherapy for ALL (vincristine, daunorubicin, L-asparaginase, prednisolone and intrathecal methotrexate) was given. Unfortunately the patient died after a sudden onset of ventricular fibrillation during an episode of pneumonia. We suggest that typhlitis may present as an initial manifestation of ALL and Giardia lamblia may play a role in its pathogenesis.
原文英語
期刊Tzu Chi Medical Journal
18
發行號2
出版狀態已發佈 - 四月 1 2006
對外發佈Yes

指紋

Typhlitis
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Giardia lamblia
Colon
Gram-Negative Anaerobic Bacteria
Asparaginase
Occult Blood
Daunorubicin
Ceftazidime
Metronidazole
Vincristine
Ventricular Fibrillation
Prednisolone
Methotrexate
Bacillus
Diarrhea
Pneumonia
Neutrophils
Fever
Fats

ASJC Scopus subject areas

  • Medicine(all)

引用此文

Chen, M. C., Lin, H. H., Yi, C. H., Chen, C. L., Huang, L. C., & Kao, R. H. (2006). Typhlitis as the initial presentation of acute lymphocytic leukemia - A case report. Tzu Chi Medical Journal, 18(2).

Typhlitis as the initial presentation of acute lymphocytic leukemia - A case report. / Chen, Ming Cheh; Lin, Hans Hsienhong; Yi, Chih Hsun; Chen, Chien Lin; Huang, Lu Chin; Kao, Ruey Ho.

於: Tzu Chi Medical Journal, 卷 18, 編號 2, 01.04.2006.

研究成果: 雜誌貢獻文章

Chen, Ming Cheh ; Lin, Hans Hsienhong ; Yi, Chih Hsun ; Chen, Chien Lin ; Huang, Lu Chin ; Kao, Ruey Ho. / Typhlitis as the initial presentation of acute lymphocytic leukemia - A case report. 於: Tzu Chi Medical Journal. 2006 ; 卷 18, 編號 2.
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