Triterpene acids from the leaves of Planchonella duclitan (Blanco) Bakhuizan

Zong-Huei Li, Shin Hun Juang, Feng Lin Hsu, Cheng Yi Wu

研究成果: 雜誌貢獻文章同行評審

58 引文 斯高帕斯(Scopus)

摘要

From the methanolic extract of the leaves of Planchonella duclitan, 2α,3α,19α,23-tetrahydroxy-13,27-cyclours-11-en-28-oic acid(1), myrianthic acid (2), 2-hydroxyursolic acid (3), ursolic acid (4), pomolic acid (5), rotundic acid (6), and jacoumaric acid (7) were isolated, and their structures were elucidated on the basis of their spectroscopic analysis. Among them, compound 1 was a new cyclopropyl ursane-type triterpene acid. Additionally, compounds 4 and 7 showed significant cytotoxicity toward human colorectal carcinoma cell line HT29 and human breast carcinoma cell line MCF-7 with IC50 values ranging from 5.8 ± 1.4 to 6.5 ± 1.9 μM.
原文英語
頁(從 - 到)1275-1280
頁數6
期刊Journal of the Chinese Chemical Society
52
發行號6
DOIs
出版狀態已發佈 - 2005

ASJC Scopus subject areas

  • 化學 (全部)

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