Treatment Results of Hodgkin's Disease from 1977 to 1991 in National Taiwan University Hospital

貢獻的翻譯標題: 台大醫院從1977至1991年對何杰金氏病的治療結果

雷 德, 許 智捷, 鍾 娜娜, 王 博民, 黃 昭源, 丁 禮莉(Lai-Lei Ting)

研究成果: 雜誌貢獻文章同行評審

摘要

Purpose: To evaluate the response and outcome of patients of Hodgkin's disease undergoing different treatment modalities.Materials and Methods: We reviewed clinical records of Hodgkin's disease who received chemotherapy (C/T), radiotherapy (R/T) or combined chemotherapy and radiotherapy (CRT) from 1977 to 1991 in National Taiwan University Hospital ( NTUH). The 5-year survival rate (SR) and 5-year freedom from relapse rate (FFR) in different stages were calculated and classified by different treatment modalities.Result: The overall 5-year survival rate (SR) and 5-year freedom from relapse rate (FFR) were summarized for stage I+Ⅱ, Ⅲ and IV diseases. In stage I+Ⅱ diseases, the SR of CIT, RIT and CRT groups were 50%, 60% and 89%; the FFR were 33%, 100% and 67% respectively. In stage Ⅲdisease, the SR of C/T and CRT groups were 72% and 90%; the FFR were 59% and 90% respectively. In stage IV disease, the SR of C/T and CRT groups were 45% and 38%; the FFR both were 38%. No statistical significance of SR was noted between CT, R/T and CRT groups in different stages. However, the FFR between C/T and R/T groups in the early stage showed statistical significance (p<O.OS). Patients with histologic subtype of lymphocyte depletion had the worst prognosis than the other 3 histologic subtypes. C/T and CRT groups bad some complications while no complication was seen in the HIT group within the 5-year follow-up.Conclusion: In our study, Hodgkin's disease was potentially curable by using either C/T, R/T, or CRT. For stage Ⅲand IV diseases, no statistical significance was noted by C/T or CRT groups. However, for early stage disease, R/T is a better treatment of choice because R/T group had better FFR and no late complication.
貢獻的翻譯標題台大醫院從1977至1991年對何杰金氏病的治療結果
原文英語
頁(從 - 到)31-38
頁數8
期刊放射治療與腫瘤學
4
發行號1
DOIs
出版狀態已發佈 - 1997
對外發佈Yes

Keywords

  • 何杰金氏病
  • 化學治療
  • 放射治療
  • 合併化學與放射治療
  • 存活率
  • 免於復發率

指紋 深入研究「台大醫院從1977至1991年對何杰金氏病的治療結果」主題。共同形成了獨特的指紋。

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