摘要

Frozen shoulder, or adhesive capsulitis, is a disease of chronic inflammation and fibrosis involving the shoulder joints. The disease is challenging in clinical practice due to painful treatment course, with disease evolution usually lasting weeks or even months, causing significant discomfort and functional loss. Botulinum toxin (BTX) has been discovered to possess abilities in pain management at various clinical diseases. The actual mechanism is still under investigation, and involves inhibition of neurotransmitter release. In addition, BTX is also found to retard process of fibrosis, which is also a key issue in pathogenesis of frozen shoulder. Therefore, we hypothesize that intra-articular injection of BTX can be an effective alternative for treatment of frozen shoulder.
原文英語
頁(從 - 到)305-307
頁數3
期刊Medical Hypotheses
77
發行號2
DOIs
出版狀態已發佈 - 八月 2011

指紋

Bursitis
Intra-Articular Injections
Shoulder Joint
Botulinum Toxins
Fibrosis
Pain Management
Therapeutics
Neurotransmitter Agents
Chronic Disease
Inflammation

ASJC Scopus subject areas

  • Medicine(all)

引用此文

Treatment of frozen shoulder with intra-articular injection of botulinum toxin in shoulder joints. / Chen, Hung Sheng; Chang, Kwang Hwa; Kang, Jiunn Horng; Hsu, Yen Hsia; Hsu, Allen Chia Lin; Chen, Shih Ching.

於: Medical Hypotheses, 卷 77, 編號 2, 08.2011, p. 305-307.

研究成果: 雜誌貢獻文章

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abstract = "Frozen shoulder, or adhesive capsulitis, is a disease of chronic inflammation and fibrosis involving the shoulder joints. The disease is challenging in clinical practice due to painful treatment course, with disease evolution usually lasting weeks or even months, causing significant discomfort and functional loss. Botulinum toxin (BTX) has been discovered to possess abilities in pain management at various clinical diseases. The actual mechanism is still under investigation, and involves inhibition of neurotransmitter release. In addition, BTX is also found to retard process of fibrosis, which is also a key issue in pathogenesis of frozen shoulder. Therefore, we hypothesize that intra-articular injection of BTX can be an effective alternative for treatment of frozen shoulder.",
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AU - Chen, Shih Ching

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