Tramadol-related psychosis in a patient with bipolar i disorder

研究成果: 雜誌貢獻文章

7 引文 (Scopus)

摘要

Introduction Tramadol hydrochloride (HCl) is a centrally acting synthetic opioid analgesic. Psychotic symptoms are relatively rare in reported adverse events. Here, we report a patient who presented with tramadol-related psychotic symptoms. Case A 59-year-old female had underlying bipolar I disorder and received lithium treatment with stable affective status. 1 month before hospitalisation, she had been taking tramadol HCl/acetaminophen for joint pain. She then developed obvious persecutory delusion. However, her clinical picture did not meet the criteria of any mood episode. After treatment of risperidone in addition to lithium, she was discharged without any psychotic symptom. She remained euthymic without any psychotic symptom on monotherapy of lithium (300 mg) three tablets once daily. Conclusions Tramadol HCl is commonly prescribed in clinical practice and psychotic symptoms related to it are uncommon. We should be careful about the rare but important adverse events while prescribing tramadol HCl.
原文英語
頁(從 - 到)126-128
頁數3
期刊Acta Neuropsychiatrica
27
發行號2
DOIs
出版狀態已發佈 - 2015

指紋

Tramadol
Bipolar Disorder
Psychotic Disorders
Lithium
Delusions
Risperidone
Arthralgia
Acetaminophen
Opioid Analgesics
Tablets
Hospitalization
Therapeutics

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

引用此文

Tramadol-related psychosis in a patient with bipolar i disorder. / Chen, Kuan Jen; Lu, Mong Liang; Shen, Winston W.

於: Acta Neuropsychiatrica, 卷 27, 編號 2, 2015, p. 126-128.

研究成果: 雜誌貢獻文章

@article{1c092ebb35a24a9d91db555969a1b755,
title = "Tramadol-related psychosis in a patient with bipolar i disorder",
abstract = "Introduction Tramadol hydrochloride (HCl) is a centrally acting synthetic opioid analgesic. Psychotic symptoms are relatively rare in reported adverse events. Here, we report a patient who presented with tramadol-related psychotic symptoms. Case A 59-year-old female had underlying bipolar I disorder and received lithium treatment with stable affective status. 1 month before hospitalisation, she had been taking tramadol HCl/acetaminophen for joint pain. She then developed obvious persecutory delusion. However, her clinical picture did not meet the criteria of any mood episode. After treatment of risperidone in addition to lithium, she was discharged without any psychotic symptom. She remained euthymic without any psychotic symptom on monotherapy of lithium (300 mg) three tablets once daily. Conclusions Tramadol HCl is commonly prescribed in clinical practice and psychotic symptoms related to it are uncommon. We should be careful about the rare but important adverse events while prescribing tramadol HCl.",
keywords = "bipolar disorder, delusions, psychosis, tramadol",
author = "Chen, {Kuan Jen} and Lu, {Mong Liang} and Shen, {Winston W.}",
year = "2015",
doi = "10.1017/neu.2014.45",
language = "English",
volume = "27",
pages = "126--128",
journal = "Acta Neuropsychiatrica",
issn = "0924-2708",
publisher = "Wiley-Blackwell",
number = "2",

}

TY - JOUR

T1 - Tramadol-related psychosis in a patient with bipolar i disorder

AU - Chen, Kuan Jen

AU - Lu, Mong Liang

AU - Shen, Winston W.

PY - 2015

Y1 - 2015

N2 - Introduction Tramadol hydrochloride (HCl) is a centrally acting synthetic opioid analgesic. Psychotic symptoms are relatively rare in reported adverse events. Here, we report a patient who presented with tramadol-related psychotic symptoms. Case A 59-year-old female had underlying bipolar I disorder and received lithium treatment with stable affective status. 1 month before hospitalisation, she had been taking tramadol HCl/acetaminophen for joint pain. She then developed obvious persecutory delusion. However, her clinical picture did not meet the criteria of any mood episode. After treatment of risperidone in addition to lithium, she was discharged without any psychotic symptom. She remained euthymic without any psychotic symptom on monotherapy of lithium (300 mg) three tablets once daily. Conclusions Tramadol HCl is commonly prescribed in clinical practice and psychotic symptoms related to it are uncommon. We should be careful about the rare but important adverse events while prescribing tramadol HCl.

AB - Introduction Tramadol hydrochloride (HCl) is a centrally acting synthetic opioid analgesic. Psychotic symptoms are relatively rare in reported adverse events. Here, we report a patient who presented with tramadol-related psychotic symptoms. Case A 59-year-old female had underlying bipolar I disorder and received lithium treatment with stable affective status. 1 month before hospitalisation, she had been taking tramadol HCl/acetaminophen for joint pain. She then developed obvious persecutory delusion. However, her clinical picture did not meet the criteria of any mood episode. After treatment of risperidone in addition to lithium, she was discharged without any psychotic symptom. She remained euthymic without any psychotic symptom on monotherapy of lithium (300 mg) three tablets once daily. Conclusions Tramadol HCl is commonly prescribed in clinical practice and psychotic symptoms related to it are uncommon. We should be careful about the rare but important adverse events while prescribing tramadol HCl.

KW - bipolar disorder

KW - delusions

KW - psychosis

KW - tramadol

UR - http://www.scopus.com/inward/record.url?scp=84927177669&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84927177669&partnerID=8YFLogxK

U2 - 10.1017/neu.2014.45

DO - 10.1017/neu.2014.45

M3 - Article

C2 - 25603153

AN - SCOPUS:84927177669

VL - 27

SP - 126

EP - 128

JO - Acta Neuropsychiatrica

JF - Acta Neuropsychiatrica

SN - 0924-2708

IS - 2

ER -