Total creatinine appearance as indicator of risk of infectious complication in peritoneal dialysis.

C. H. Wu, C. C. Huang, M. S. Wu, C. W. Yang, J. Y. Huang, J. T. Fang, M. L. Leu

研究成果: 雜誌貢獻文章

3 引文 斯高帕斯(Scopus)

摘要

Peritonitis and exit-site infections are the main causes of complications in peritoneal dialysis. Death due to infectious complication is also one of the major causes of drop-out. The underlying cause of infection may include malnutrition. Total creatinine appearance (TCA) may reflect overall nutritional status. We determined TCA from the daily dialysate, urine, and estimated gut creatinine of patients and normalized it to actual body weight (nTCA). We examined the relationship between nTCA and the incidence of infection, and between nTCA and infection-related survival. The study included 323 adult patients in a single dialysis center. The mean nTCA of all patients was 19.73 +/- 4.75 mg/kg/day. The patients with an nTCA below 1 standard deviation from the mean (nTCA <14.98 mg/kg/day) had a significantly higher peritonitis and exit-site infection rate (p <0.01) and a higher chance of drop-out owing to infection-related complications (p <0.0001). Our study concluded that the adult patient with malnutrition (nTCA <14.98 mg/kg/day) has higher risk of infection.

原文英語
頁(從 - 到)219-222
頁數4
期刊Advances in peritoneal dialysis. Conference on Peritoneal Dialysis
16
出版狀態已發佈 - 2000
對外發佈Yes

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