摘要
Cartilage matrix is damaged in diseased states such as osteoarthritis while adult articular cartilage does not have the capacity to repair structural damage. A least invasive mean to diagnose these diseased states of human articular cartilage with a high spatial resolution is thus highly desired. In this paper we present our harmonic generation microscopic studies on the human articular cartilage samples. Without any staining third and second harmonic generation can provide strong contrast in chondrocytes and collagen matrix respectively. Our study indicates the high capability of harmonic generation microscopy for future articular cartilage disease diagnosis.
原文 | 英語 |
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主出版物標題 | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
卷 | 7183 |
DOIs | |
出版狀態 | 已發佈 - 2009 |
對外發佈 | Yes |
事件 | Multiphoton Microscopy in the Biomedical Sciences IX - San Jose, CA, 美国 持續時間: 一月 25 2009 → 一月 27 2009 |
其他
其他 | Multiphoton Microscopy in the Biomedical Sciences IX |
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國家 | 美国 |
城市 | San Jose, CA |
期間 | 1/25/09 → 1/27/09 |
ASJC Scopus subject areas
- Applied Mathematics
- Computer Science Applications
- Electrical and Electronic Engineering
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics