THE SYNTHESIS AND OPIATE ACTIVITY OF HUMAN β‐ENDORPHIN ANALOGS: Substituted at Residue Positions 27 and 31

James Blake, Liang‐Fu ‐F Tseng, Wen‐Chang ‐C Chang, Choh Hao Li

研究成果: 雜誌貢獻 › 文章

10 引文 (Scopus)

摘要

Four analogs of human β‐endorphin have been synthesized and their opiate activities have been determined. One of the analogs, [27‐phenylalanine, 31‐glycine]‐βh‐endorphin, was shown to possess an analgesic potency greater than that of the natural peptide.
原文英語
頁（從 - 到）323-328
頁數6
期刊International Journal of Peptide and Protein Research
卷11
發行號5
DOIs
出版狀態已發佈 - 一月 1 1978
對外發佈Yes

指紋

Opiate Alkaloids
Endorphins
Human Activities
Analgesics
Peptides

ASJC Scopus subject areas

  • Biochemistry

引用此文

THE SYNTHESIS AND OPIATE ACTIVITY OF HUMAN β‐ENDORPHIN ANALOGS : Substituted at Residue Positions 27 and 31. / Blake, James; Tseng, Liang‐Fu ‐F; Chang, Wen‐Chang ‐C; Li, Choh Hao.

於: International Journal of Peptide and Protein Research, 卷 11, 編號 5, 01.01.1978, p. 323-328.

研究成果: 雜誌貢獻 › 文章

Blake, J, Tseng, LFF, Chang, WCC & Li, CH 1978, 'THE SYNTHESIS AND OPIATE ACTIVITY OF HUMAN β‐ENDORPHIN ANALOGS: Substituted at Residue Positions 27 and 31', International Journal of Peptide and Protein Research, 卷 11, 編號 5, 頁 323-328. https://doi.org/10.1111/j.1399-3011.1978.tb02856.x
Blake J, Tseng LFF, Chang WCC, Li CH. THE SYNTHESIS AND OPIATE ACTIVITY OF HUMAN β‐ENDORPHIN ANALOGS: Substituted at Residue Positions 27 and 31. International Journal of Peptide and Protein Research. 1978 1月 1;11(5):323-328. https://doi.org/10.1111/j.1399-3011.1978.tb02856.x
Blake, James ; Tseng, Liang‐Fu ‐F ; Chang, Wen‐Chang ‐C ; Li, Choh Hao. / THE SYNTHESIS AND OPIATE ACTIVITY OF HUMAN β‐ENDORPHIN ANALOGS : Substituted at Residue Positions 27 and 31. 於: International Journal of Peptide and Protein Research. 1978 ; 卷 11, 編號 5. 頁 323-328.
@article{1f87a150d35546c4ba43a612fb3568b8,
title = "THE SYNTHESIS AND OPIATE ACTIVITY OF HUMAN β‐ENDORPHIN ANALOGS: Substituted at Residue Positions 27 and 31",
abstract = "Four analogs of human β‐endorphin have been synthesized and their opiate activities have been determined. One of the analogs, [27‐phenylalanine, 31‐glycine]‐βh‐endorphin, was shown to possess an analgesic potency greater than that of the natural peptide.",
keywords = "opiate activity, peptide synthesis, β‐endorphin",
author = "James Blake and Tseng, {Liang‐Fu ‐F} and Chang, {Wen‐Chang ‐C} and Li, {Choh Hao}",
year = "1978",
month = "1",
day = "1",
doi = "10.1111/j.1399-3011.1978.tb02856.x",
language = "English",
volume = "11",
pages = "323--328",
journal = "International Journal of Peptide and Protein Research",
issn = "0367-8377",
publisher = "Wiley-Blackwell",
number = "5",

}

TY - JOUR

T1 - THE SYNTHESIS AND OPIATE ACTIVITY OF HUMAN β‐ENDORPHIN ANALOGS

T2 - Substituted at Residue Positions 27 and 31

AU - Blake, James

AU - Tseng, Liang‐Fu ‐F

AU - Chang, Wen‐Chang ‐C

AU - Li, Choh Hao

PY - 1978/1/1

Y1 - 1978/1/1

N2 - Four analogs of human β‐endorphin have been synthesized and their opiate activities have been determined. One of the analogs, [27‐phenylalanine, 31‐glycine]‐βh‐endorphin, was shown to possess an analgesic potency greater than that of the natural peptide.

AB - Four analogs of human β‐endorphin have been synthesized and their opiate activities have been determined. One of the analogs, [27‐phenylalanine, 31‐glycine]‐βh‐endorphin, was shown to possess an analgesic potency greater than that of the natural peptide.

KW - opiate activity

KW - peptide synthesis

KW - β‐endorphin

UR - http://www.scopus.com/inward/record.url?scp=0018194775&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018194775&partnerID=8YFLogxK

U2 - 10.1111/j.1399-3011.1978.tb02856.x

DO - 10.1111/j.1399-3011.1978.tb02856.x

M3 - Article

C2 - 681076

AN - SCOPUS:0018194775

VL - 11

SP - 323

EP - 328

JO - International Journal of Peptide and Protein Research

JF - International Journal of Peptide and Protein Research

SN - 0367-8377

IS - 5

ER -

存取文件