The serologic decoy receptor 3 (DcR3) levels are associated with slower disease progression in HIV-1/AIDS patients

Yu Ting Lin, Chia Hung Yen, Heng Li Chen, Yi Jen Liao, I. Feng Lin, Marcelo Chen, Yu Ching Lan, Shao Yuan Chuang, Shie Liang Hsieh, Yi Ming Arthur Chen

研究成果: 雜誌貢獻文章

2 引文 斯高帕斯(Scopus)

摘要

Background/Purpose: The decoy receptor 3 (DcR3) is a member of the tumor necrosis factor receptor (TNFR) super-family. It counteracts the biological effects of Fas ligands and inhibits apoptosis. The goals of this study were to understand the associations between serologic DcR3 (sDcR3) levels and different human immunodeficiency virus type 1 (HIV-1) subtypes, as well as the AIDS disease progression. Methods: Serum samples from 61 HIV/AIDS patients, who had been followed up every 6 months for 3 years, were collected. sDcR3 levels were quantified using an enzyme immunoassay (EIA). Results: The sDcR3 levels in patients with HIV-1 subtype B were significantly higher than those in patients infected with subtype CRF01_AE (. p
原文英語
頁(從 - 到)498-503
頁數6
期刊Journal of the Formosan Medical Association = Taiwan yi zhi
114
發行號6
DOIs
出版狀態已發佈 - 六月 1 2015

ASJC Scopus subject areas

  • Medicine(all)

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