The Role of High Sensitivity C-Reactive Protein and Coronary Artery Calcium as Predictors of the Long-term Prognosis in Men with Coronary Artery Disease

Zhong Xuan Ye, Po Hsun Huang, Hsin Bang Leu, Tao Cheng Wu, Shing Jong Lin, Jaw Wen Chen

研究成果: 雜誌貢獻文章

摘要

Purpose: Measurements of coronary artery calcium (CAC) and of high sensitivity C-reactive protein (hsCRP) are used to predict the risk of cardiovascular events in patients with coronary artery disease (CAD). The aim of our study was to investigate the hypothesis that combining the hsCRP level and CAC score can increase the predictive value of these parameters for future cardiovascular events in male patients with suspected CAD. Methods: We included 90 male patients with stable angina. We measured their serum hsCRP and CAC scores by using electron-beam computerized tomography. These baseline parameters were correlated to the clinical cardiovascular events within the follow-up period. Results: During the follow-up period of up to 50 months (median 27 months), 13 major cardiovascular events were recorded. In multivariate regression analysis, after being adjusted for conventional risk factors, hsCRP and CAC score, hsCRP level was the only independent predictor of cardiovascular events. Further analysis was performed among the four groups classified by CAC score (CAC score ≥100 or

原文英語
頁(從 - 到)39-42
頁數4
期刊Journal of Experimental and Clinical Medicine(Taiwan)
4
發行號1
DOIs
出版狀態已發佈 - 二月 2012

指紋

C-Reactive Protein
Coronary Artery Disease
Coronary Vessels
Calcium
X Ray Computed Tomography
Stable Angina
Multivariate Analysis
Regression Analysis
Serum

ASJC Scopus subject areas

  • Medicine(all)

引用此文

The Role of High Sensitivity C-Reactive Protein and Coronary Artery Calcium as Predictors of the Long-term Prognosis in Men with Coronary Artery Disease. / Ye, Zhong Xuan; Huang, Po Hsun; Leu, Hsin Bang; Wu, Tao Cheng; Lin, Shing Jong; Chen, Jaw Wen.

於: Journal of Experimental and Clinical Medicine(Taiwan), 卷 4, 編號 1, 02.2012, p. 39-42.

研究成果: 雜誌貢獻文章

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abstract = "Purpose: Measurements of coronary artery calcium (CAC) and of high sensitivity C-reactive protein (hsCRP) are used to predict the risk of cardiovascular events in patients with coronary artery disease (CAD). The aim of our study was to investigate the hypothesis that combining the hsCRP level and CAC score can increase the predictive value of these parameters for future cardiovascular events in male patients with suspected CAD. Methods: We included 90 male patients with stable angina. We measured their serum hsCRP and CAC scores by using electron-beam computerized tomography. These baseline parameters were correlated to the clinical cardiovascular events within the follow-up period. Results: During the follow-up period of up to 50 months (median 27 months), 13 major cardiovascular events were recorded. In multivariate regression analysis, after being adjusted for conventional risk factors, hsCRP and CAC score, hsCRP level was the only independent predictor of cardiovascular events. Further analysis was performed among the four groups classified by CAC score (CAC score ≥100 or",
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AU - Huang, Po Hsun

AU - Leu, Hsin Bang

AU - Wu, Tao Cheng

AU - Lin, Shing Jong

AU - Chen, Jaw Wen

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N2 - Purpose: Measurements of coronary artery calcium (CAC) and of high sensitivity C-reactive protein (hsCRP) are used to predict the risk of cardiovascular events in patients with coronary artery disease (CAD). The aim of our study was to investigate the hypothesis that combining the hsCRP level and CAC score can increase the predictive value of these parameters for future cardiovascular events in male patients with suspected CAD. Methods: We included 90 male patients with stable angina. We measured their serum hsCRP and CAC scores by using electron-beam computerized tomography. These baseline parameters were correlated to the clinical cardiovascular events within the follow-up period. Results: During the follow-up period of up to 50 months (median 27 months), 13 major cardiovascular events were recorded. In multivariate regression analysis, after being adjusted for conventional risk factors, hsCRP and CAC score, hsCRP level was the only independent predictor of cardiovascular events. Further analysis was performed among the four groups classified by CAC score (CAC score ≥100 or

AB - Purpose: Measurements of coronary artery calcium (CAC) and of high sensitivity C-reactive protein (hsCRP) are used to predict the risk of cardiovascular events in patients with coronary artery disease (CAD). The aim of our study was to investigate the hypothesis that combining the hsCRP level and CAC score can increase the predictive value of these parameters for future cardiovascular events in male patients with suspected CAD. Methods: We included 90 male patients with stable angina. We measured their serum hsCRP and CAC scores by using electron-beam computerized tomography. These baseline parameters were correlated to the clinical cardiovascular events within the follow-up period. Results: During the follow-up period of up to 50 months (median 27 months), 13 major cardiovascular events were recorded. In multivariate regression analysis, after being adjusted for conventional risk factors, hsCRP and CAC score, hsCRP level was the only independent predictor of cardiovascular events. Further analysis was performed among the four groups classified by CAC score (CAC score ≥100 or

KW - Atherosclerosis

KW - Coronary artery calcium

KW - Coronary artery disease

KW - High sensitivity C-reactive protein

KW - Male sex

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