The risk prediction model and risk index for colorectal cancer

Yi Cheng Liu, Fung Chang Sung, Ling Ling Hsieh, Reiping Tang, Chih Ching Yeh

研究成果: 雜誌貢獻文章同行評審

3 引文 斯高帕斯(Scopus)

摘要

Objectives: Various prediction models or indices for cancer risk have been developed in Western countries, but no such instruments are available in Taiwan. Colorectal cancer is the third leading cause of cancer deaths in Taiwan, thus it is essential to establish a prediction model or risk index for the prevention of colorectal cancer. Methods: The risk prediction model was established by a case-control study using multivariate logistic regression. Individual odds ratios (OR) for each risk factor were transformed into a risk point. An overall risk point was calculated as an index by summing all risk points for the related risk factors. The risk index was divided into seven categories according to the distribution of the total risk points. Results: In the risk prediction models, ten and nine significant risk factors were identified for males and females, respectively. With the exception of alcohol consumption in females, nine risk factors were identical in both genders, including race, occupation, physical activity, coffee intake, and the consumption of white meat, seafood, vegetables, and fruits, and the method of cooking of meat. After checking the strata for the selected risk factors, individuals can acquire their total risk points using the sum of the risk points for each risk factor. Referring to the level of the risk index by matched total risk points, individuals can recognize their risk level for the development of colorectal cancer. Conclusions: This study has established a risk prediction model and risk index for colorectal cancer in Taiwan. It is a simple and convenient method to assess colorectal cancer risk for the population in Taiwan. A prospective cohort study, however, is needed to help validate the accuracy of this risk prediction model and risk index.
原文英語
頁(從 - 到)1-12
頁數12
期刊Taiwan Journal of Public Health
27
發行號1
出版狀態已發佈 - 二月 2008
對外發佈

Keywords

  • Colorectal cancer
  • Risk index
  • Risk prediction model
  • Taiwan

ASJC Scopus subject areas

  • 公共衛生、環境和職業健康

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