The prevalence of Fusobacterium nucleatum before and after periodontal treatment of periodontitis patients in Taiwanese

Ching-Zong Wu, Wen-Chih Wu, Fumiya Harada, Keng-Liang Ou, Rey-Yue Yuan

研究成果: 雜誌貢獻文章


The Fusobacterium nucleatum is the pathogens not only in periodontitis but also in cardiac infection ((Socransky and Haffajee, 2002.) F. nucleatum may serves as an enabler to other microrganisms to spread systemically ( Yann Fardinin et al 2011) The purpose of this study is to find the prevalence of the F.nucleatun in periodontitis before and after scaling and root planning and to find the efficacy of periodontal treatment to eradicate the pathogens . Nineteen severe adult periodontitis patients were included and approved by ethic review board. The bacteria were sampling from saliva and pocket via paper point respectively before and 4-6 weeks after scaling and root planning. The collected samples were processed by RT-PCR to quantify the microbes. The result indicated high percentage of periodontitis patients (>98%) having F.nucleatun in high amount not only in saliva (220,167) but also in periodontal pocket area (721,058). The total amount of F. nucleatun decreased dramatically in amount not only in saliva ( 50 %) but also in pocket ( 79%) after periodontal treatment . In conclusion, delicate periodontal treatment can eradicate effectively the possible oral cavity pathogens which could be harmful to cardiovascular system.
期刊Journal of International Society of Microbiota
出版狀態已發佈 - 九月 19 2016