The outcome of patients requiring multiple extracorporeal membrane oxygenation: How many runs of ECMO is reasonable?

Heng Wen Chou, Te I. Chang, Chih Hsien Wang, Nai Kuan Chou, Nai Hsin Chi, Shu Chien Huang, I. Hui Wu, Chih Yang Chan, Lee Mei Ponge, Ya Chen Wang, Yih Sharng Chen

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)

摘要

Background: Extracorporeal membrane oxygenation (ECMO) has been proven effective in life support for patients with refractory cardiopulmonary failure. Deteriorating patients who have removed their first ECMO support and required second or more courses of ECMO support have rarely been discussed. Methods and results: All the records of the patients who experienced at least 2 courses of ECMO during single admission were retrieved. Survival was defined as survival to discharge. Demographic data and clinical information were compared between survival and nonsurvival groups. There were 86 patients who received at least 2 courses of ECMO in the 20-year database, and 27 (31.3%) were <18 years old. Of them, 87.3% received 2 runs of ECMO, 10.4% 3 runs, and 2.3% 4 runs. Overall survival rate was 30.2%. The survival rate for patients with 2 runs of ECMO was 33.3% (25 out of 75), 11.1% (1 out of 9) for 3 runs, and 0% (0 out of 2) for 4 runs. Multivariate analysis revealed that only ARF with hemodialysis was the independent risk factor. Conclusions: The decision to perform repeated ECMO implantation is a complex and difficult process. Despite the arguments debating the consumption of resources and increased complications, there are still nearly 1 out of 3 patients who will survive to discharge. More than 2 courses of ECMO may be carefully considered for further rescue.

原文英語
頁(從 - 到)288-293
頁數6
期刊International Journal of Artificial Organs
39
發行號6
DOIs
出版狀態已發佈 - 六月 1 2016

ASJC Scopus subject areas

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomaterials
  • Biomedical Engineering

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    Chou, H. W., Chang, T. I., Wang, C. H., Chou, N. K., Chi, N. H., Huang, S. C., Wu, I. H., Chan, C. Y., Ponge, L. M., Wang, Y. C., & Chen, Y. S. (2016). The outcome of patients requiring multiple extracorporeal membrane oxygenation: How many runs of ECMO is reasonable? International Journal of Artificial Organs, 39(6), 288-293. https://doi.org/10.5301/ijao.5000511