The octamers d(CGCGCGCG) and d(CGCATGCG) both crystallize as Z‐DNA in the same hexagonal lattice

Satoshi Fujii, Andrew H.‐J Wang, Gary J. Quigley, Henk Westerink, Gijs Van Der Marel, Jacques H. Van Boom, Alexander Rich

研究成果: 雜誌貢獻文章同行評審

42 引文 斯高帕斯(Scopus)

摘要

Both (dC‐dG)4 and d(CGCATGCG) crystallize in hexagonal lattices and their three‐dimensional structure has been solved by x‐ray diffraction analysis. Both molecules are found to form Z‐DNA, although the fine details of the structure cannot be visualized due to the statistical disordering of the molecules along the c‐axis, which is brought about by the symmetry constraints of the space group. This represents the first time in which the unmodified dinucleotide sequences CpAp and TpGp have been found to form Z‐DNA in a crystalline lattice.

原文英語
頁(從 - 到)243-250
頁數8
期刊Biopolymers
24
發行號1
DOIs
出版狀態已發佈 - 1月 1985
對外發佈

ASJC Scopus subject areas

  • 生物物理學
  • 生物化學
  • 生物材料
  • 有機化學

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