The influence of autonomic interventions on the sleep-wake-related changes in gastric myoelectrical activity in rats

Y. M. Huang, C. C H Yang, C. J. Lai, T. B J Kuo

研究成果: 雜誌貢獻文章

1 引文 斯高帕斯(Scopus)

摘要

Background Significant changes in autonomic activity occur at sleep-wake transitions and constitute an ideal setting for investigating the modulatory role of the autonomic nervous system on gastric myoelectrical activity (GMA). Methods Using continuous power spectral analysis of electroencephalogram, electromyogram, and electrogastromyogram (EGMG) data from freely moving rats that had undergone chemical sympathetomy and/or truncal vagotomy, sleep-wake-related fluctuations in GMA were compared among the intervention groups. Key Results The pattern and extent of fluctuations in EGMG power across the sleep-wake states was blunted most significantly in rats undergoing both chemical sympathectomy and truncal vagotomy. The effect of these interventions also varied with respect to the transition between different sleep-wake states. The most prominent influences were observed between active waking and quiet sleep and between paradoxical sleep and quiet sleep. Conclusions & Inferences The sleep-wake-related fluctuations in EGMG power are a result of joint contributions from both sympathetic and vagal innervation. Vagotomy mainly resulted in a reduction in EGMG power, while the role of sympathetic innervation was unveiled by vagotomy and this was reflected most obviously in the extent of the fluctuations in EGMG power.
原文英語
期刊Neurogastroenterology and Motility
23
發行號6
DOIs
出版狀態已發佈 - 六月 2011
對外發佈Yes

ASJC Scopus subject areas

  • Endocrine and Autonomic Systems
  • Gastroenterology
  • Physiology

指紋 深入研究「The influence of autonomic interventions on the sleep-wake-related changes in gastric myoelectrical activity in rats」主題。共同形成了獨特的指紋。

  • 引用此