The Inducible Role of Ambient Particulate Matter in Cancer Progression via Oxidative Stress-Mediated Reactive Oxygen Species Pathways: A Recent Perception

Chiang-Wen Lee, Thi Thuy Tien Vo, Ching-Zong Wu, Miao-Ching Chi, Chieh-Mo Lin, Mei-Ling Fang, I-Ta Lee

研究成果: 雜誌貢獻回顧型文獻同行評審

1 引文 斯高帕斯(Scopus)

摘要

Cancer is one of the leading causes of premature death and overall death in the world. On the other hand, fine particulate matter, which is less than 2.5 microns in aerodynamic diameter, is a global health problem due to its small diameter but high toxicity. Accumulating evidence has demonstrated the positive associations between this pollutant with both lung and non-lung cancer processes. However, the underlying mechanisms are yet to be elucidated. The present review summarizes and analyzes the most recent findings on the relationship between fine particulate matter and various types of cancer along with the oxidative stress mechanisms as its possible carcinogenic mechanisms. Also, promising antioxidant therapies against cancer induced by this poison factor are discussed.
原文英語
文章編號2505
頁(從 - 到)1-21
頁數21
期刊Cancers
12
發行號9
DOIs
出版狀態已發佈 - 九月 2020

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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