The histological maturity of regenerating mucosa of healed duodenal ulcer and ulcer recurrence after treatment with H2-antagonist

S. Pan, C. H. Liao

研究成果: 雜誌貢獻 › 文章

11 引文 (Scopus)

摘要

We investigated the relationship between the histological maturity of regenerating mucosa of healed duodenal ulcer and ulcer recurrence, after treatment with an H2-antagonist. Duodenal ulcer patients were given H2-antagonists (either cimetidine or famotidine) for 4 wk of therapy. Fifty-two (77.6%) of the 67 patients were healed endoscopically. The histological state of the regenerating mucosa of healed duodenal ulcer was divided into three categories: good, fair, and poor patterns. Of the 52 healed patients, 15 achieved a good histological pattern. None of these 15 patients had a recurrence 3 months later. However, nine of the 37 patients with a fair or poor pattern of regenerating mucosa had a recurrence 3 months after healing (p = 0.034). We concluded that a duodenal ulcer should be treated until the regenerating mucosa of the healed ulcer reaches a good histological pattern, so as to prevent the recurrence of the ulcer.
原文英語
頁（從 - 到）949-952
頁數4
期刊American Journal of Gastroenterology
卷85
發行號8
出版狀態已發佈 - 1990

指紋

Duodenal Ulcer
Ulcer
Mucous Membrane
Recurrence
Famotidine
Therapeutics
Cimetidine

ASJC Scopus subject areas

  • Gastroenterology

引用此文

The histological maturity of regenerating mucosa of healed duodenal ulcer and ulcer recurrence after treatment with H2-antagonist. / Pan, S.; Liao, C. H.

於: American Journal of Gastroenterology, 卷 85, 編號 8, 1990, p. 949-952.

研究成果: 雜誌貢獻 › 文章

Pan, S & Liao, CH 1990, 'The histological maturity of regenerating mucosa of healed duodenal ulcer and ulcer recurrence after treatment with H2-antagonist', American Journal of Gastroenterology, 卷 85, 編號 8, 頁 949-952.
Pan S, Liao CH. The histological maturity of regenerating mucosa of healed duodenal ulcer and ulcer recurrence after treatment with H2-antagonist. American Journal of Gastroenterology. 1990;85(8):949-952.
Pan, S. ; Liao, C. H. / The histological maturity of regenerating mucosa of healed duodenal ulcer and ulcer recurrence after treatment with H2-antagonist. 於: American Journal of Gastroenterology. 1990 ; 卷 85, 編號 8. 頁 949-952.
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