The feasibility of an approximate irregular field dose distribution simulation program applied to a respiratory motion compensation system

Lai Lei Ting, Ai Ho Liao, Muthusankar Ganesan, Chia Chun Kuo, Hsiao Wei Yu, Po Jung Chen, Shiu Chen Jeng, Jeng Fong Chiou, Ho Chiao Chuang

研究成果: 雜誌貢獻文章同行評審

摘要

Purpose: This study optimized our previously proposed simulation program for the approximate irregular field dose distribution (SPAD) and applied it to a respiratory motion compensation system (RMCS) and respiratory motion simulation system (RMSS). The main purpose was to rapidly analyze the two-dimensional dose distribution and evaluate the compensation effect of the RMCS during radiotherapy. Methods: This study modified the SPAD to improve the rapid analysis of the dose distribution. In the experimental setup, four different respiratory signal patterns were input to the RMSS for actuation, and an ultrasound image tracking algorithm was used to capture the real-time respiratory displacement, which was input to the RMCS for actuation. A linear accelerator simultaneously irradiated the EBT3 film. The gamma passing rate was used to verify the dose similarity between the EBT3 film and the SPAD, and conformity index (CI) and compensation rate (CR) were used to quantify the compensation effect. Results: The Gamma passing rates were 70.48–81.39% (2%/2mm) and 88.23–96.23% (5%/3mm) for various collimator opening patterns. However, the passing rates of the SPAD and EBT3 film ranged from 61.85% to 99.85% at each treatment time point. Under the four different respiratory signal patterns, CR ranged between 21% and 75%. After compensation, the CI for 85%, 90%, and 95% isodose constraints were 0.78, 0.57, and 0.12, respectively. Conclusions: This study has demonstrated that the dose change during each stage of the treatment process can be analyzed rapidly using the improved SPAD. After compensation, applying the RMCS can reduce the treatment errors caused by respiratory movements.

原文英語
頁(從 - 到)117-126
頁數10
期刊Physica Medica
88
DOIs
出版狀態已發佈 - 八月 2021

ASJC Scopus subject areas

  • 生物物理學
  • 放射學、核子醫學和影像學
  • 物理與天文學 (全部)

指紋

深入研究「The feasibility of an approximate irregular field dose distribution simulation program applied to a respiratory motion compensation system」主題。共同形成了獨特的指紋。

引用此