TY - JOUR
T1 - The evolution of peroxisomal and mitochondrial alanine
T2 - Glyoxylate aminotransferase 1 in mammalian liver
AU - Takada, Yoshikazu
AU - Noguchi, Tomoo
PY - 1982/9/16
Y1 - 1982/9/16
N2 - Immunological distances of alanine: glyoxylate aminotransferase 1 (serine:pyruvate aminotransferase) in mitochondria or peroxisomes from eight different mammalian liver were determined with rabbit anti-serum against the mitochondrial enzyme of rat liver by microcomplement fixation. Results suggest that heterotopic alanine:glyoxylate aminotransferase 1 are orthologous proteins and their subcellular localization and substrate specificity changed during rapid molecular evolution.
AB - Immunological distances of alanine: glyoxylate aminotransferase 1 (serine:pyruvate aminotransferase) in mitochondria or peroxisomes from eight different mammalian liver were determined with rabbit anti-serum against the mitochondrial enzyme of rat liver by microcomplement fixation. Results suggest that heterotopic alanine:glyoxylate aminotransferase 1 are orthologous proteins and their subcellular localization and substrate specificity changed during rapid molecular evolution.
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U2 - 10.1016/0006-291X(82)91844-7
DO - 10.1016/0006-291X(82)91844-7
M3 - Article
C2 - 6816225
AN - SCOPUS:0020485238
VL - 108
SP - 153
EP - 157
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
SN - 0006-291X
IS - 1
ER -