The effect of temperature and standings can cause deviations in prostate specific antigen (PSA) assays

Chiu Lan Hsieh, Ching Yuan Chang, Wang Sheng Ko, Bor Shah Chen, Kuan Chou Chen, Robert Y. Peng

研究成果: 雜誌貢獻文章同行評審

摘要

Blood samples were assayed for PSA values immediately after sampled or by standing for an assigned period. Variation of the free- (f), total- (t) values, and the free to total (f/t) ratios were determined. Mathematical models were used to interpret the phenomena of deviation. Smaller values of PSA values changed randomly with time and temperature of standings, resulting in varying f/t ratios, while larger initial PSA values were relatively unaffected to any significant extent. Model interpreted that the changes of PSA values might be caused by higher temperature and time of standings, and conformational participation was also possible.

原文英語
頁(從 - 到)2485-2496
頁數12
期刊Analytical Letters
40
發行號13
DOIs
出版狀態已發佈 - 一月 2007

ASJC Scopus subject areas

  • 分析化學
  • 生物化學、遺傳與分子生物學 (全部)
  • 生物化學

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