The effect of a Computerized pediatric dosing decision support system on pediatric dosing errors

Jing Yi Hou, Kuei Ju Cheng, Kuan Jen Bai, Hsiang Yin Chen, Wen Hao Wu, You Meei Lin, Man Tzu Marcie Wu

研究成果: 雜誌貢獻文章

2 引文 斯高帕斯(Scopus)

摘要

Children are more susceptible to medication errors because of differences in pharmacokinetics and pharmacodynamics compared to adults. Weight changes are common with growth in children and computer systems frequently are not updated with current information, which result in inaccurate weight-based dosing and thus harm children. This study evaluated the impact of a Computerized Physician Order Entry system with standardized pediatric dosing decision support (PDDS) function on reducing pediatric dosing errors. Outpatient prescriptions were analyzed from January to March during 2010 and 2011. The total number of pediatric prescriptions was 72,431 and 80,532 prior to and after system implementation, respectively. Out of 72,431 prescriptions, 1617 (2.23%) dosing errors were retrospectively detected by the system, whereas 15 dosing errors (0.02%) were detected by pharmacists prior to system implementation. Incorporating the system into practice resulted in a total of 210 successfully blocked dosing near misses, including 14 potentially fatal and 11 serious near misses. The final dosing error rate was significantly reduced from 2.23% to 0.66% (p <0.001). A 10-fold increase of the near miss correction rate (0.02% vs. 0.26%, p <0.001) was observed. The Computerized Physician Order Entry system with standardized pediatric dosing decision support system provided real-time warning and significantly decreased the dose error rate among pediatric patients.
原文英語
頁(從 - 到)286-291
頁數6
期刊Journal of Food and Drug Analysis
21
發行號3
DOIs
出版狀態已發佈 - 九月 2013

ASJC Scopus subject areas

  • Food Science
  • Pharmacology

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