The effect of a Computerized pediatric dosing decision support system on pediatric dosing errors

Jing Yi Hou, Kuei Ju Cheng, Kuan Jen Bai, Hsiang Yin Chen, Wen Hao Wu, You Meei Lin, Man Tzu Marcie Wu

研究成果: 雜誌貢獻文章

2 引文 (Scopus)

摘要

Children are more susceptible to medication errors because of differences in pharmacokinetics and pharmacodynamics compared to adults. Weight changes are common with growth in children and computer systems frequently are not updated with current information, which result in inaccurate weight-based dosing and thus harm children. This study evaluated the impact of a Computerized Physician Order Entry system with standardized pediatric dosing decision support (PDDS) function on reducing pediatric dosing errors. Outpatient prescriptions were analyzed from January to March during 2010 and 2011. The total number of pediatric prescriptions was 72,431 and 80,532 prior to and after system implementation, respectively. Out of 72,431 prescriptions, 1617 (2.23%) dosing errors were retrospectively detected by the system, whereas 15 dosing errors (0.02%) were detected by pharmacists prior to system implementation. Incorporating the system into practice resulted in a total of 210 successfully blocked dosing near misses, including 14 potentially fatal and 11 serious near misses. The final dosing error rate was significantly reduced from 2.23% to 0.66% (p <0.001). A 10-fold increase of the near miss correction rate (0.02% vs. 0.26%, p <0.001) was observed. The Computerized Physician Order Entry system with standardized pediatric dosing decision support system provided real-time warning and significantly decreased the dose error rate among pediatric patients.
原文英語
頁(從 - 到)286-291
頁數6
期刊Journal of Food and Drug Analysis
21
發行號3
DOIs
出版狀態已發佈 - 九月 2013

指紋

decision support systems
physicians
Pediatrics
child growth
Medical Order Entry Systems
Prescriptions
pharmacology
pharmacokinetics
drug therapy
Computer Systems
Weights and Measures
dosage
Medication Errors
Pharmacists
Outpatients
Pharmacokinetics
Growth

ASJC Scopus subject areas

  • Food Science
  • Pharmacology

引用此文

The effect of a Computerized pediatric dosing decision support system on pediatric dosing errors. / Hou, Jing Yi; Cheng, Kuei Ju; Bai, Kuan Jen; Chen, Hsiang Yin; Wu, Wen Hao; Lin, You Meei; Wu, Man Tzu Marcie.

於: Journal of Food and Drug Analysis, 卷 21, 編號 3, 09.2013, p. 286-291.

研究成果: 雜誌貢獻文章

@article{ab11e21979be4ddc8cdb406ba275ec88,
title = "The effect of a Computerized pediatric dosing decision support system on pediatric dosing errors",
abstract = "Children are more susceptible to medication errors because of differences in pharmacokinetics and pharmacodynamics compared to adults. Weight changes are common with growth in children and computer systems frequently are not updated with current information, which result in inaccurate weight-based dosing and thus harm children. This study evaluated the impact of a Computerized Physician Order Entry system with standardized pediatric dosing decision support (PDDS) function on reducing pediatric dosing errors. Outpatient prescriptions were analyzed from January to March during 2010 and 2011. The total number of pediatric prescriptions was 72,431 and 80,532 prior to and after system implementation, respectively. Out of 72,431 prescriptions, 1617 (2.23{\%}) dosing errors were retrospectively detected by the system, whereas 15 dosing errors (0.02{\%}) were detected by pharmacists prior to system implementation. Incorporating the system into practice resulted in a total of 210 successfully blocked dosing near misses, including 14 potentially fatal and 11 serious near misses. The final dosing error rate was significantly reduced from 2.23{\%} to 0.66{\%} (p <0.001). A 10-fold increase of the near miss correction rate (0.02{\%} vs. 0.26{\%}, p <0.001) was observed. The Computerized Physician Order Entry system with standardized pediatric dosing decision support system provided real-time warning and significantly decreased the dose error rate among pediatric patients.",
keywords = "Computerized Physician Order Entry (CPOE), Medication safety, Pediatric dose, Pediatrics",
author = "Hou, {Jing Yi} and Cheng, {Kuei Ju} and Bai, {Kuan Jen} and Chen, {Hsiang Yin} and Wu, {Wen Hao} and Lin, {You Meei} and Wu, {Man Tzu Marcie}",
year = "2013",
month = "9",
doi = "10.1016/j.jfda.2013.07.006",
language = "English",
volume = "21",
pages = "286--291",
journal = "Journal of Food and Drug Analysis",
issn = "1021-9498",
publisher = "Elsevier Taiwan LLC",
number = "3",

}

TY - JOUR

T1 - The effect of a Computerized pediatric dosing decision support system on pediatric dosing errors

AU - Hou, Jing Yi

AU - Cheng, Kuei Ju

AU - Bai, Kuan Jen

AU - Chen, Hsiang Yin

AU - Wu, Wen Hao

AU - Lin, You Meei

AU - Wu, Man Tzu Marcie

PY - 2013/9

Y1 - 2013/9

N2 - Children are more susceptible to medication errors because of differences in pharmacokinetics and pharmacodynamics compared to adults. Weight changes are common with growth in children and computer systems frequently are not updated with current information, which result in inaccurate weight-based dosing and thus harm children. This study evaluated the impact of a Computerized Physician Order Entry system with standardized pediatric dosing decision support (PDDS) function on reducing pediatric dosing errors. Outpatient prescriptions were analyzed from January to March during 2010 and 2011. The total number of pediatric prescriptions was 72,431 and 80,532 prior to and after system implementation, respectively. Out of 72,431 prescriptions, 1617 (2.23%) dosing errors were retrospectively detected by the system, whereas 15 dosing errors (0.02%) were detected by pharmacists prior to system implementation. Incorporating the system into practice resulted in a total of 210 successfully blocked dosing near misses, including 14 potentially fatal and 11 serious near misses. The final dosing error rate was significantly reduced from 2.23% to 0.66% (p <0.001). A 10-fold increase of the near miss correction rate (0.02% vs. 0.26%, p <0.001) was observed. The Computerized Physician Order Entry system with standardized pediatric dosing decision support system provided real-time warning and significantly decreased the dose error rate among pediatric patients.

AB - Children are more susceptible to medication errors because of differences in pharmacokinetics and pharmacodynamics compared to adults. Weight changes are common with growth in children and computer systems frequently are not updated with current information, which result in inaccurate weight-based dosing and thus harm children. This study evaluated the impact of a Computerized Physician Order Entry system with standardized pediatric dosing decision support (PDDS) function on reducing pediatric dosing errors. Outpatient prescriptions were analyzed from January to March during 2010 and 2011. The total number of pediatric prescriptions was 72,431 and 80,532 prior to and after system implementation, respectively. Out of 72,431 prescriptions, 1617 (2.23%) dosing errors were retrospectively detected by the system, whereas 15 dosing errors (0.02%) were detected by pharmacists prior to system implementation. Incorporating the system into practice resulted in a total of 210 successfully blocked dosing near misses, including 14 potentially fatal and 11 serious near misses. The final dosing error rate was significantly reduced from 2.23% to 0.66% (p <0.001). A 10-fold increase of the near miss correction rate (0.02% vs. 0.26%, p <0.001) was observed. The Computerized Physician Order Entry system with standardized pediatric dosing decision support system provided real-time warning and significantly decreased the dose error rate among pediatric patients.

KW - Computerized Physician Order Entry (CPOE)

KW - Medication safety

KW - Pediatric dose

KW - Pediatrics

UR - http://www.scopus.com/inward/record.url?scp=84885627360&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84885627360&partnerID=8YFLogxK

U2 - 10.1016/j.jfda.2013.07.006

DO - 10.1016/j.jfda.2013.07.006

M3 - Article

AN - SCOPUS:84885627360

VL - 21

SP - 286

EP - 291

JO - Journal of Food and Drug Analysis

JF - Journal of Food and Drug Analysis

SN - 1021-9498

IS - 3

ER -