The complete nucleotide sequence of the growth-hormone gene from the common carp (Cyprinus carpio)

Chien Shun Chiou, Huang Tsu Chen, Wen Chang Chang

研究成果: 雜誌貢獻文章

54 引文 (Scopus)

摘要

We have isolated and sequenced a phage clone from a common carp (Cyprinus carpio) genomic library that carries a gene encoding growth hormone (GH). This gene consists of five exons and four introns spanning a region of about 3 kilobasepairs. Its exons correspond with one of two reported cDNAs of carp GH except for nine differences in the nucleotide sequence, while the encoded amino-acid sequences are identical. The sequence upstream from the transcription start point contains two tandem repeats of AACTCTCATG (from -85 to -62) and the typical TATA box. All the introns start with a consensus GT dinucleotide and end with AG. The arrangement of exons and introns is very similar to that seen in mammalian GH, but quite different from the GH genes of rainbow trout and Atlantic salmon.
原文英語
頁(從 - 到)91-94
頁數4
期刊BBA - Gene Structure and Expression
1087
發行號1
DOIs
出版狀態已發佈 - 九月 10 1990
對外發佈Yes

指紋

Carps
Growth Hormone
Nucleotides
Genes
Introns
Exons
Salmo salar
TATA Box
Bacteriophages
Tandem Repeat Sequences
Gene encoding
Genomic Library
Oncorhynchus mykiss
Transcription
Amino Acid Sequence
Complementary DNA
Clone Cells
Amino Acids

ASJC Scopus subject areas

  • Structural Biology
  • Biophysics
  • Biochemistry
  • Genetics

引用此文

The complete nucleotide sequence of the growth-hormone gene from the common carp (Cyprinus carpio). / Chiou, Chien Shun; Chen, Huang Tsu; Chang, Wen Chang.

於: BBA - Gene Structure and Expression, 卷 1087, 編號 1, 10.09.1990, p. 91-94.

研究成果: 雜誌貢獻文章

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N2 - We have isolated and sequenced a phage clone from a common carp (Cyprinus carpio) genomic library that carries a gene encoding growth hormone (GH). This gene consists of five exons and four introns spanning a region of about 3 kilobasepairs. Its exons correspond with one of two reported cDNAs of carp GH except for nine differences in the nucleotide sequence, while the encoded amino-acid sequences are identical. The sequence upstream from the transcription start point contains two tandem repeats of AACTCTCATG (from -85 to -62) and the typical TATA box. All the introns start with a consensus GT dinucleotide and end with AG. The arrangement of exons and introns is very similar to that seen in mammalian GH, but quite different from the GH genes of rainbow trout and Atlantic salmon.

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