The association between serum asymmetric dimethylarginine and coronary atherosclerotic plaque in an asymptomatic population

Chun Yao Huang, Jong Shiuan Yeh, Chun Ming Shih, Feng Yen Lin, Yung Ta Kao, Nai Wen Tsao, Wen Tien Hsiao, Jaw Wen Chen, Nen Chung Chang, Kou-Gi Shyu

研究成果: 雜誌貢獻文章

摘要

Asymmetric dimethylarginine (ADMA) is an endogenous competitive inhibitor of nitric oxide synthase and is independently associated with poor cardiovascular outcomes. However, the direct relationship between serum ADMA level and the extent of subclinical coronary atherosclerotic plaque has never been investigated. In total, 130 consecutive asymptomatic Taiwanese subjects (mean age, 55.6±10 years), who received a health screening evaluation, were enrolled. Coronary plaque detected by computed tomography coronary angiography (CTCA) was observed in 85 (65.4%) of 130 individuals. Patients with coronary plaque had a higher ADMA level (1.16±1.15 μmol/L vs. 0.42 ± 0.33 μmol /L, p
原文英語
頁(從 - 到)236-243
頁數8
期刊Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry
12
發行號3
出版狀態已發佈 - 2012

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Immunology and Allergy
  • Pharmacology

指紋 深入研究「The association between serum asymmetric dimethylarginine and coronary atherosclerotic plaque in an asymptomatic population」主題。共同形成了獨特的指紋。

  • 引用此