The association between postpartum depression and air pollution during pregnancy and postpartum period: A national population study in Taiwan

Ping Shih, Chih Da Wu, Tung Liang Chiang, Pau Chung Chen, Ta Chen Su, Tsun Jen Cheng, Yi Hua Chen, Yue Leon Guo

研究成果: 雜誌貢獻文章同行評審

摘要

Epidemiological evidence shows the association between air pollutants and several mental health outcomes, including depression, sleep disturbance, dementia, childhood neurodevelopment and suicide. Pregnant women are believed to be more susceptible and vulnerable to environmental pollutants, and postpartum depression (PPD) is a prevalent debilitating mental disorder. However, data on the effects of exposure to air pollution during pregnancy and postpartum period on the risk of PPD remain limited. This study aimed to evaluate the association between exposure to ambient air pollution during pregnancy and postpartum period and the incidence of PPD. The Taiwan Birth Cohort Study recruited representative 12% of all newborn in 2005 and their mothers by two-stage stratified sampling, including 21 248 mother-infant pairs. The occurrence of PPD was assessed by a self-reported questionnaire. Exposure to air pollutants during pregnancy and postpartum period was estimated using hybrid kriging/land-use regression (LUR) and integrated LUR-machine learning model based on data from the air monitoring stations. Logistic regression was then conducted to determine adjusted odds ratios (aORs) of PPD in relation to air pollutants. A total of 21 188 women were included in the final analysis, among whom 3,648 (17.2%) developed PPD within 6 months postpartum. The occurrence of PPD was significantly related to exposure to ambient concentrations of nitrogen dioxide (NO2) during first trimester after adjustment [aOR: 1.081 per interquartile range (10.67 ppb), 95% confidence interval: 1.003, 1.165], but not to particulate matter ≤2.5 µm in diameter or carbon monoxide. Exposure to ambient NO2 during early pregnancy was significantly related to the occurrence of PPD among the women investigated in this population-based study.

原文英語
文章編號084021
期刊Environmental Research Letters
16
發行號8
DOIs
出版狀態已發佈 - 八月 2021

ASJC Scopus subject areas

  • 可再生能源、永續發展與環境
  • 環境科學 (全部)
  • 公共衛生、環境和職業健康

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