The application of signal average ECG in the prediction of recurrences after catheter ablation of ventricular arrhythmias in arrhythmogenic right ventricular dysplasia/cardiomyopathy

Ying Chieh Liao, Fa Po Chung, Yenn Jiang Lin, Shih Lin Chang, Li-Wei Lo, Yu Feng Hu, Ta Chuan Tuan, Tze Fan Chao, Jo Nan Liao, Chin Yu Lin, Yao Ting Chang, Ming-Hsiung Hsieh, Shih Ann Chen

研究成果: 雜誌貢獻 › 文章

2 引文 (Scopus)

摘要

Background: The changes of signal averaged ECG (SAECG) in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) undergoing radiofrequency catheter ablation (RFCA) of ventricular arrhythmias (VAs) remains unknown. Methods: Between 2010 and 2014, a total of 81 ARVD/C patients underwent endocardial and/or epicardial RFCA for drug-refractory VAs. Seventy patients (mean age 46.2. ±. 14.1. years, 37 males) achieving acute procedure success (negative inducibility) were enrolled. Baseline characteristics, non-invasive examinations and SAECG (before and 3. months after RFCA) were collected retrospectively. Results: After successful RFCA, the electrical parameters of SAECG changed in 39 patients (55.7%), including 28 patients (40%) with electrical regression (group 1), and 11 patients (15.7%) with electrical progression (group 3). Thirty-one patients (44.3%) showed no significant SAECG change (group 2). During a mean follow-up of 17.8. ±. 10.7. months, 23 patients (32.9%) had VA recurrences, including 4 in group 1, 12 in group 2, and 7 in group 3. In comparisons with groups 2 and 3, group 1 patients had a significantly better VA recurrence-free survival (P = 0.02). In multivariable Cox regression analysis, electrical regression was found to be associated with fewer VA recurrences (P = 0.02, OR: 0.28, 95% CI: 0.10-. 0.83). Conclusions: Electrical regression of SAECG after RFCA in ARVD/C was found to be associated with fewer VA recurrences.
原文英語
頁（從 - 到）168-173
期刊International Journal of Cardiology
卷236
DOIs
出版狀態已發佈 - 六月 1 2017

指紋

Arrhythmogenic Right Ventricular Dysplasia
Catheter Ablation
Cardiac Arrhythmias
Electrocardiography
Recurrence
Regression Analysis

ASJC Scopus subject areas

  • Medicine(all)
  • Cardiology and Cardiovascular Medicine

引用此文

The application of signal average ECG in the prediction of recurrences after catheter ablation of ventricular arrhythmias in arrhythmogenic right ventricular dysplasia/cardiomyopathy. / Liao, Ying Chieh; Chung, Fa Po; Lin, Yenn Jiang; Chang, Shih Lin; Lo, Li-Wei; Hu, Yu Feng; Tuan, Ta Chuan; Chao, Tze Fan; Liao, Jo Nan; Lin, Chin Yu; Chang, Yao Ting; Hsieh, Ming-Hsiung; Chen, Shih Ann.

於: International Journal of Cardiology, 卷 236, 01.06.2017, p. 168-173.

研究成果: 雜誌貢獻 › 文章

Liao, YC, Chung, FP, Lin, YJ, Chang, SL, Lo, L-W, Hu, YF, Tuan, TC, Chao, TF, Liao, JN, Lin, CY, Chang, YT, Hsieh, M-H & Chen, SA 2017, 'The application of signal average ECG in the prediction of recurrences after catheter ablation of ventricular arrhythmias in arrhythmogenic right ventricular dysplasia/cardiomyopathy', International Journal of Cardiology, 卷 236, 頁 168-173. https://doi.org/10.1016/j.ijcard.2017.01.087
Liao YC, Chung FP, Lin YJ, Chang SL, Lo L-W, Hu YF 等. The application of signal average ECG in the prediction of recurrences after catheter ablation of ventricular arrhythmias in arrhythmogenic right ventricular dysplasia/cardiomyopathy. International Journal of Cardiology. 2017 6月 1;236:168-173. https://doi.org/10.1016/j.ijcard.2017.01.087
Liao, Ying Chieh ; Chung, Fa Po ; Lin, Yenn Jiang ; Chang, Shih Lin ; Lo, Li-Wei ; Hu, Yu Feng ; Tuan, Ta Chuan ; Chao, Tze Fan ; Liao, Jo Nan ; Lin, Chin Yu ; Chang, Yao Ting ; Hsieh, Ming-Hsiung ; Chen, Shih Ann. / The application of signal average ECG in the prediction of recurrences after catheter ablation of ventricular arrhythmias in arrhythmogenic right ventricular dysplasia/cardiomyopathy. 於: International Journal of Cardiology. 2017 ; 卷 236. 頁 168-173.
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title = "The application of signal average ECG in the prediction of recurrences after catheter ablation of ventricular arrhythmias in arrhythmogenic right ventricular dysplasia/cardiomyopathy",
abstract = "Background: The changes of signal averaged ECG (SAECG) in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) undergoing radiofrequency catheter ablation (RFCA) of ventricular arrhythmias (VAs) remains unknown. Methods: Between 2010 and 2014, a total of 81 ARVD/C patients underwent endocardial and/or epicardial RFCA for drug-refractory VAs. Seventy patients (mean age 46.2. ±. 14.1. years, 37 males) achieving acute procedure success (negative inducibility) were enrolled. Baseline characteristics, non-invasive examinations and SAECG (before and 3. months after RFCA) were collected retrospectively. Results: After successful RFCA, the electrical parameters of SAECG changed in 39 patients (55.7{\%}), including 28 patients (40{\%}) with electrical regression (group 1), and 11 patients (15.7{\%}) with electrical progression (group 3). Thirty-one patients (44.3{\%}) showed no significant SAECG change (group 2). During a mean follow-up of 17.8. ±. 10.7. months, 23 patients (32.9{\%}) had VA recurrences, including 4 in group 1, 12 in group 2, and 7 in group 3. In comparisons with groups 2 and 3, group 1 patients had a significantly better VA recurrence-free survival (P = 0.02). In multivariable Cox regression analysis, electrical regression was found to be associated with fewer VA recurrences (P = 0.02, OR: 0.28, 95{\%} CI: 0.10-. 0.83). Conclusions: Electrical regression of SAECG after RFCA in ARVD/C was found to be associated with fewer VA recurrences.",
keywords = "ARVD/C, Catheter ablation, Electrical regression, SAECG, Ventricular arrhythmia",
author = "Liao, {Ying Chieh} and Chung, {Fa Po} and Lin, {Yenn Jiang} and Chang, {Shih Lin} and Li-Wei Lo and Hu, {Yu Feng} and Tuan, {Ta Chuan} and Chao, {Tze Fan} and Liao, {Jo Nan} and Lin, {Chin Yu} and Chang, {Yao Ting} and Ming-Hsiung Hsieh and Chen, {Shih Ann}",
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T1 - The application of signal average ECG in the prediction of recurrences after catheter ablation of ventricular arrhythmias in arrhythmogenic right ventricular dysplasia/cardiomyopathy

AU - Liao, Ying Chieh

AU - Chung, Fa Po

AU - Lin, Yenn Jiang

AU - Chang, Shih Lin

AU - Lo, Li-Wei

AU - Hu, Yu Feng

AU - Tuan, Ta Chuan

AU - Chao, Tze Fan

AU - Liao, Jo Nan

AU - Lin, Chin Yu

AU - Chang, Yao Ting

AU - Hsieh, Ming-Hsiung

AU - Chen, Shih Ann

PY - 2017/6/1

Y1 - 2017/6/1

N2 - Background: The changes of signal averaged ECG (SAECG) in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) undergoing radiofrequency catheter ablation (RFCA) of ventricular arrhythmias (VAs) remains unknown. Methods: Between 2010 and 2014, a total of 81 ARVD/C patients underwent endocardial and/or epicardial RFCA for drug-refractory VAs. Seventy patients (mean age 46.2. ±. 14.1. years, 37 males) achieving acute procedure success (negative inducibility) were enrolled. Baseline characteristics, non-invasive examinations and SAECG (before and 3. months after RFCA) were collected retrospectively. Results: After successful RFCA, the electrical parameters of SAECG changed in 39 patients (55.7%), including 28 patients (40%) with electrical regression (group 1), and 11 patients (15.7%) with electrical progression (group 3). Thirty-one patients (44.3%) showed no significant SAECG change (group 2). During a mean follow-up of 17.8. ±. 10.7. months, 23 patients (32.9%) had VA recurrences, including 4 in group 1, 12 in group 2, and 7 in group 3. In comparisons with groups 2 and 3, group 1 patients had a significantly better VA recurrence-free survival (P = 0.02). In multivariable Cox regression analysis, electrical regression was found to be associated with fewer VA recurrences (P = 0.02, OR: 0.28, 95% CI: 0.10-. 0.83). Conclusions: Electrical regression of SAECG after RFCA in ARVD/C was found to be associated with fewer VA recurrences.

AB - Background: The changes of signal averaged ECG (SAECG) in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) undergoing radiofrequency catheter ablation (RFCA) of ventricular arrhythmias (VAs) remains unknown. Methods: Between 2010 and 2014, a total of 81 ARVD/C patients underwent endocardial and/or epicardial RFCA for drug-refractory VAs. Seventy patients (mean age 46.2. ±. 14.1. years, 37 males) achieving acute procedure success (negative inducibility) were enrolled. Baseline characteristics, non-invasive examinations and SAECG (before and 3. months after RFCA) were collected retrospectively. Results: After successful RFCA, the electrical parameters of SAECG changed in 39 patients (55.7%), including 28 patients (40%) with electrical regression (group 1), and 11 patients (15.7%) with electrical progression (group 3). Thirty-one patients (44.3%) showed no significant SAECG change (group 2). During a mean follow-up of 17.8. ±. 10.7. months, 23 patients (32.9%) had VA recurrences, including 4 in group 1, 12 in group 2, and 7 in group 3. In comparisons with groups 2 and 3, group 1 patients had a significantly better VA recurrence-free survival (P = 0.02). In multivariable Cox regression analysis, electrical regression was found to be associated with fewer VA recurrences (P = 0.02, OR: 0.28, 95% CI: 0.10-. 0.83). Conclusions: Electrical regression of SAECG after RFCA in ARVD/C was found to be associated with fewer VA recurrences.

KW - ARVD/C

KW - Catheter ablation

KW - Electrical regression

KW - SAECG

KW - Ventricular arrhythmia

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