Testosterone modulates preattentive sensory processing and involuntary attention switches to emotional voices

Chenyi Chen, Chin Yau Chen, Chih Yung Yang, Chi Hung Lin, Yawei Cheng

研究成果: 雜誌貢獻文章

8 引文 (Scopus)

摘要

Testosterone is capable of altering facial threat processing. Voices, similar to faces, convey social information. We hypothesized that administering a single dose of testosterone would change voice perception in humans. In a placebo-controlled, randomly assigned, double-blind crossover design, we administered a single dose of testosterone or placebo to 18 healthy female volunteers and used a passive auditory oddball paradigm. The mismatch negativity (MMN) and P3a in responses to fearfully, happily, and neutrally spoken syllables dada and acoustically matched nonvocal sounds were analyzed, indicating preattentive sensory processing and involuntary attention switches. Results showed that testosterone administration had a trend to shorten the peak latencies of happy MMN and significantly enhanced the amplitudes of happy and fearful P3a, whereas the happyand fearful-derived nonvocal MMN and P3a remained unaffected. These findings demonstrated acute effect of testosterone on the neural dynamics of voice perception. Administering a single dose of testosterone modulates preattentive sensory processing and involuntary attention switches in response to emotional voices.
原文英語
頁(從 - 到)1842-1849
頁數8
期刊Journal of Neurophysiology
113
發行號6
DOIs
出版狀態已發佈 - 三月 15 2015
對外發佈Yes

指紋

Testosterone
Placebos
Cross-Over Studies
Healthy Volunteers

ASJC Scopus subject areas

  • Neuroscience(all)
  • Physiology

引用此文

Testosterone modulates preattentive sensory processing and involuntary attention switches to emotional voices. / Chen, Chenyi; Chen, Chin Yau; Yang, Chih Yung; Lin, Chi Hung; Cheng, Yawei.

於: Journal of Neurophysiology, 卷 113, 編號 6, 15.03.2015, p. 1842-1849.

研究成果: 雜誌貢獻文章

Chen, Chenyi ; Chen, Chin Yau ; Yang, Chih Yung ; Lin, Chi Hung ; Cheng, Yawei. / Testosterone modulates preattentive sensory processing and involuntary attention switches to emotional voices. 於: Journal of Neurophysiology. 2015 ; 卷 113, 編號 6. 頁 1842-1849.
@article{10e3d335df414fcfba22c6e7fa084c57,
title = "Testosterone modulates preattentive sensory processing and involuntary attention switches to emotional voices",
abstract = "Testosterone is capable of altering facial threat processing. Voices, similar to faces, convey social information. We hypothesized that administering a single dose of testosterone would change voice perception in humans. In a placebo-controlled, randomly assigned, double-blind crossover design, we administered a single dose of testosterone or placebo to 18 healthy female volunteers and used a passive auditory oddball paradigm. The mismatch negativity (MMN) and P3a in responses to fearfully, happily, and neutrally spoken syllables dada and acoustically matched nonvocal sounds were analyzed, indicating preattentive sensory processing and involuntary attention switches. Results showed that testosterone administration had a trend to shorten the peak latencies of happy MMN and significantly enhanced the amplitudes of happy and fearful P3a, whereas the happyand fearful-derived nonvocal MMN and P3a remained unaffected. These findings demonstrated acute effect of testosterone on the neural dynamics of voice perception. Administering a single dose of testosterone modulates preattentive sensory processing and involuntary attention switches in response to emotional voices.",
keywords = "Mismatch negativity, MMN, P3a, Testosterone, Voice",
author = "Chenyi Chen and Chen, {Chin Yau} and Yang, {Chih Yung} and Lin, {Chi Hung} and Yawei Cheng",
year = "2015",
month = "3",
day = "15",
doi = "10.1152/jn.00587.2014",
language = "English",
volume = "113",
pages = "1842--1849",
journal = "Journal of Neurophysiology",
issn = "0022-3077",
publisher = "American Physiological Society",
number = "6",

}

TY - JOUR

T1 - Testosterone modulates preattentive sensory processing and involuntary attention switches to emotional voices

AU - Chen, Chenyi

AU - Chen, Chin Yau

AU - Yang, Chih Yung

AU - Lin, Chi Hung

AU - Cheng, Yawei

PY - 2015/3/15

Y1 - 2015/3/15

N2 - Testosterone is capable of altering facial threat processing. Voices, similar to faces, convey social information. We hypothesized that administering a single dose of testosterone would change voice perception in humans. In a placebo-controlled, randomly assigned, double-blind crossover design, we administered a single dose of testosterone or placebo to 18 healthy female volunteers and used a passive auditory oddball paradigm. The mismatch negativity (MMN) and P3a in responses to fearfully, happily, and neutrally spoken syllables dada and acoustically matched nonvocal sounds were analyzed, indicating preattentive sensory processing and involuntary attention switches. Results showed that testosterone administration had a trend to shorten the peak latencies of happy MMN and significantly enhanced the amplitudes of happy and fearful P3a, whereas the happyand fearful-derived nonvocal MMN and P3a remained unaffected. These findings demonstrated acute effect of testosterone on the neural dynamics of voice perception. Administering a single dose of testosterone modulates preattentive sensory processing and involuntary attention switches in response to emotional voices.

AB - Testosterone is capable of altering facial threat processing. Voices, similar to faces, convey social information. We hypothesized that administering a single dose of testosterone would change voice perception in humans. In a placebo-controlled, randomly assigned, double-blind crossover design, we administered a single dose of testosterone or placebo to 18 healthy female volunteers and used a passive auditory oddball paradigm. The mismatch negativity (MMN) and P3a in responses to fearfully, happily, and neutrally spoken syllables dada and acoustically matched nonvocal sounds were analyzed, indicating preattentive sensory processing and involuntary attention switches. Results showed that testosterone administration had a trend to shorten the peak latencies of happy MMN and significantly enhanced the amplitudes of happy and fearful P3a, whereas the happyand fearful-derived nonvocal MMN and P3a remained unaffected. These findings demonstrated acute effect of testosterone on the neural dynamics of voice perception. Administering a single dose of testosterone modulates preattentive sensory processing and involuntary attention switches in response to emotional voices.

KW - Mismatch negativity

KW - MMN

KW - P3a

KW - Testosterone

KW - Voice

UR - http://www.scopus.com/inward/record.url?scp=84930844789&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84930844789&partnerID=8YFLogxK

U2 - 10.1152/jn.00587.2014

DO - 10.1152/jn.00587.2014

M3 - Article

C2 - 25540221

AN - SCOPUS:84930844789

VL - 113

SP - 1842

EP - 1849

JO - Journal of Neurophysiology

JF - Journal of Neurophysiology

SN - 0022-3077

IS - 6

ER -