Systematic review of the clinical performance of connective tissue graft and guided tissue regeneration in the treatment of gingival recessions of miller's classification grades I and II

Hui Yuan Ko, Hsein K. Lu

研究成果: 雜誌貢獻回顧型文獻

5 引文 (Scopus)

摘要

Background/Purpose: The objective of this meta-analysis was to assess and compare the effectiveness of connective tissue graft (CTG) and guided tissue regeneration (GTR) in treating patients with gingival recessions of Miller's classification grades I and II. Methods: Nineteen clinical studies that met prestated inclusion criteria were screened from 250 initial articles for the systematic analysis of the clinical efficacies of CTG and GTR according to four clinical variables: recession depth reduction; clinical attachment gain; keratinized tissue gain; and probing depth reduction. The heterogeneity and weighted mean difference were calculated using a statistical package for meta-analysis. Results: In the follow-up period shorter than 12 months, CTG resulted in more keratinized tissue than GTR (p <0.05). In the follow-up period of 12 months or longer, CTG resulted in significantly greater reduction in recession depth, more keratinized tissue gain, and less probing depth reduction than GTR (p <0.05). Conclusion: With regard to recession depth reduction and keratinized tissue gain in the treatment of Miller's class I or II gingival recession, CTG was statistically significantly more effective than GTR.
原文英語
頁(從 - 到)63-71
頁數9
期刊Journal of Experimental and Clinical Medicine(Taiwan)
2
發行號2
DOIs
出版狀態已發佈 - 四月 2010

指紋

Guided Tissue Regeneration
Gingival Recession
Connective Tissue
Transplants
Meta-Analysis
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

引用此文

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title = "Systematic review of the clinical performance of connective tissue graft and guided tissue regeneration in the treatment of gingival recessions of miller's classification grades I and II",
abstract = "Background/Purpose: The objective of this meta-analysis was to assess and compare the effectiveness of connective tissue graft (CTG) and guided tissue regeneration (GTR) in treating patients with gingival recessions of Miller's classification grades I and II. Methods: Nineteen clinical studies that met prestated inclusion criteria were screened from 250 initial articles for the systematic analysis of the clinical efficacies of CTG and GTR according to four clinical variables: recession depth reduction; clinical attachment gain; keratinized tissue gain; and probing depth reduction. The heterogeneity and weighted mean difference were calculated using a statistical package for meta-analysis. Results: In the follow-up period shorter than 12 months, CTG resulted in more keratinized tissue than GTR (p <0.05). In the follow-up period of 12 months or longer, CTG resulted in significantly greater reduction in recession depth, more keratinized tissue gain, and less probing depth reduction than GTR (p <0.05). Conclusion: With regard to recession depth reduction and keratinized tissue gain in the treatment of Miller's class I or II gingival recession, CTG was statistically significantly more effective than GTR.",
keywords = "Connective tissue graft, Gingival recession, Guided tissue regeneration, Miller's classification, Root coverage",
author = "Ko, {Hui Yuan} and Lu, {Hsein K.}",
year = "2010",
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AU - Ko, Hui Yuan

AU - Lu, Hsein K.

PY - 2010/4

Y1 - 2010/4

N2 - Background/Purpose: The objective of this meta-analysis was to assess and compare the effectiveness of connective tissue graft (CTG) and guided tissue regeneration (GTR) in treating patients with gingival recessions of Miller's classification grades I and II. Methods: Nineteen clinical studies that met prestated inclusion criteria were screened from 250 initial articles for the systematic analysis of the clinical efficacies of CTG and GTR according to four clinical variables: recession depth reduction; clinical attachment gain; keratinized tissue gain; and probing depth reduction. The heterogeneity and weighted mean difference were calculated using a statistical package for meta-analysis. Results: In the follow-up period shorter than 12 months, CTG resulted in more keratinized tissue than GTR (p <0.05). In the follow-up period of 12 months or longer, CTG resulted in significantly greater reduction in recession depth, more keratinized tissue gain, and less probing depth reduction than GTR (p <0.05). Conclusion: With regard to recession depth reduction and keratinized tissue gain in the treatment of Miller's class I or II gingival recession, CTG was statistically significantly more effective than GTR.

AB - Background/Purpose: The objective of this meta-analysis was to assess and compare the effectiveness of connective tissue graft (CTG) and guided tissue regeneration (GTR) in treating patients with gingival recessions of Miller's classification grades I and II. Methods: Nineteen clinical studies that met prestated inclusion criteria were screened from 250 initial articles for the systematic analysis of the clinical efficacies of CTG and GTR according to four clinical variables: recession depth reduction; clinical attachment gain; keratinized tissue gain; and probing depth reduction. The heterogeneity and weighted mean difference were calculated using a statistical package for meta-analysis. Results: In the follow-up period shorter than 12 months, CTG resulted in more keratinized tissue than GTR (p <0.05). In the follow-up period of 12 months or longer, CTG resulted in significantly greater reduction in recession depth, more keratinized tissue gain, and less probing depth reduction than GTR (p <0.05). Conclusion: With regard to recession depth reduction and keratinized tissue gain in the treatment of Miller's class I or II gingival recession, CTG was statistically significantly more effective than GTR.

KW - Connective tissue graft

KW - Gingival recession

KW - Guided tissue regeneration

KW - Miller's classification

KW - Root coverage

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