Synthesis of Five‐Membered Ring Heteroaryl Pyridines from Heteroaryllithium and N‐Ethoxycarbonylpyridinium Chlorides

Long‐Li ‐L Lai, Li‐Hua ‐H Shin, Pen‐Yuan ‐Y Lin, Jy‐Shih ‐S Wang, Min‐Jen ‐J Shiao

研究成果: 雜誌貢獻文章

2 引文 斯高帕斯(Scopus)

摘要

Furylpyridines, thienylpyridines, and imidazolylpyridines were obtained regioselectively in 40‐67% yields from the reaction of heteroaryllithiums with N‐ethoxycarbonylpyridinium chloride or N‐ethoxycarbonyl‐3‐methylpyridinium chloride in the presence of Cul in a catalytic amount at −78 °C or −50°C, then followed by oxidation. The regioselectivity of this reaction depended upon temperature of the reaction and the nature of heteroaryllithiurn.

原文英語
頁(從 - 到)75-79
頁數5
期刊Journal of the Chinese Chemical Society
41
發行號1
DOIs
出版狀態已發佈 - 1994
對外發佈Yes

ASJC Scopus subject areas

  • Chemistry(all)

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