Synthesis, Lipid Peroxidation and Cytotoxic Evaluation of 10-Substituted 1,5-Dichloro-9(10H)-anthracenone Derivatives

Hsu-Shan Huang (发明人)

研究成果: 專利

摘要

The present invention is the synthesis of a series of 1,5-dichloro-9(10H)-anthracenones bearing O-linked and N-linked substituents in the 10-position. These compounds were evaluated for their ability to inhibit the growth of the human oral epidermoid carcinoma cells (KB cell line), human cervical carcinoma cells of ME 180 (GBM 8401) and Chinese hamster ovary cells (CHO), respectively. In addition, redox property of the compounds for inhibition of lipid peroxidation in model membranes was determined.
原文英語
出版狀態已發佈 - 2003

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