SYNTHESIS AND OPIATE ACTIVITY OF HUMAN β‐ENDORPHIN ANALOGS WITH VARIOUS CHAIN LENGTHS

Hin‐Wing ‐W Yeung, Donald Yamashiro, Wen‐Chang ‐C Chang, Choh Hao Li

研究成果: 雜誌貢獻文章

13 引文 斯高帕斯(Scopus)

摘要

The synthesis of βh‐endorphin* ‐(1–15), ‐(1–21), ‐(1–26), ‐(1–28) and ‐(1–29) have been accomplished by the solid‐phase method. The opiate activities of the peptides were measured in the guinea pig ileum assay. Their relative potencies were βh‐endorphin (βh‐EP), 1.00; Met‐enkephalin, 0.25; βh‐EP‐(1–15), 0.17; βh‐EP‐(1–21), 0.46; βh‐EP‐(1–26), 0.48; βh‐EP‐(1–28), 0.89; βh‐EP‐(1–29), 1.04.
原文英語
頁(從 - 到)42-46
頁數5
期刊International Journal of Peptide and Protein Research
12
發行號1
DOIs
出版狀態已發佈 - 一月 1 1978
對外發佈Yes

    指紋

ASJC Scopus subject areas

  • Biochemistry

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