Synthesis and evaluation of antibacterial activities of 5,7-dihydroxycoumarin derivatives

Yi Ping Chin, Wei Jan Huang, Feng-Lin Hsu, Mei Hsiang Lin, Yuh Ling Lin

研究成果: 雜誌貢獻文章同行評審

11 引文 斯高帕斯(Scopus)

摘要

This study examines the synthesis and antibacterial activities of 5,7-dihydroxycoumarin derivatives, whose structures were confirmed using analytical and spectral data. Twenty compounds were tested for their antibacterial activities against five microbial species such as E. coli, S. aureus, K. pneumonia, P. aeruginosa, and S. typhimurium were studied. Compounds 5 and 12 exhibited the most potent activity against Staphylococcus aureus with a MIC value of 2.5 μg/mL for each of the compounds.

原文英語
頁(從 - 到)386-393
頁數8
期刊Archiv der Pharmazie
344
發行號6
DOIs
出版狀態已發佈 - 六月 2011

ASJC Scopus subject areas

  • 藥物發現
  • 藥學科學

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