Surface nanoporosity of β-type Ti-25Nb-25Zr alloy for the enhancement of protein adsorption and cell response

Her Hsiung Huang, Chia Ping Wu, Ying Sui Sun, Wei En Yang, Mau Chin Lin, Tzu Hsin Lee

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23 引文 斯高帕斯(Scopus)

摘要

This paper outlines a simple method for the electrochemical anodization of β-type Ti-25Nb-25Zr (Ti25Nb25Zr) alloy with a low elastic modulus (approximately 70. GPa) to alter its surface topography for bone implant applications. Surface characteristics including topography, roughness, hydrophilicity, and protein adsorption (fibronectin and albumin) were investigated. Human bone marrow mesenchymal stem cell responses, including adhesion, migration, proliferation, and mineralization, were also evaluated. The experimental results demonstrate that the electrochemical anodization process produced a nanoporous surface (pore size <. 15. nm) on Ti25Nb25Zr alloy. This surface nanotopography did not alter the surface roughness or hydrophilicity of the Ti25Nb25Zr alloy but was capable of enhancing biological responses, including protein adsorption, cell adhesion, cell migration, cell proliferation, and cell mineralization. The created surface nanoporosity on β-type Ti25Nb25Zr alloy has a high potential for bone implant applications.
原文英語
頁(從 - 到)206-212
頁數7
期刊Surface and Coatings Technology
259
發行號PB
DOIs
出版狀態已發佈 - 1月 1 2014

ASJC Scopus subject areas

  • 化學 (全部)
  • 凝聚態物理學
  • 表面和介面
  • 表面、塗料和薄膜
  • 材料化學

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