Surface Characteristics and Cell Adhesion Behaviors of the Anodized Biomedical Stainless Steel

Heng-Jui Hsu, Chia-Yu Wu, Bai-Hung Huang, Chi-Hsun Tsai, Takashi Saito, Keng-Liang Ou, Yen-Chun Chuo, Kuan-Ling Lin, Pei-Wen Peng

研究成果: 雜誌貢獻文章同行評審


In this study, an electrochemical anodizing method was applied as surface modification of the 316L biomedical stainless steel (BSS). The surface properties, microstructural characteristics, and biocompatibility responses of the anodized 316L BSS specimens were elucidated through scanning electron microscopy, X-ray photoelectron spectroscopy, X-ray diffractometry, transmission electron microscopy, and in vitro cell culture assay. Analytical results revealed that the oxide layer of dichromium trioxide (Cr2O3) was formed on the modified 316L BSS specimens after the different anodization modifications. Moreover, a dual porous (micro/nanoporous) topography can also be discovered on the surface of the modified 316L BSS specimens. The microstructure of the anodized oxide layer was composed of amorphous austenite phase and nano-Cr2O3. Furthermore, in vitro cell culture assay also demonstrated that the osteoblast-like cells (MG-63) on the anodized 316L BSS specimens were completely adhered and covered as compared with the unmodified 316L BSS specimen. As a result, the anodized 316L BSS with a dual porous (micro/nanoporous) oxide layer has great potential to induce cell adhesion and promote bone formation.

頁(從 - 到)6275
期刊Applied Sciences (Switzerland)
出版狀態已發佈 - 九月 9 2020

ASJC Scopus subject areas

  • Materials Science(all)
  • Instrumentation
  • Engineering(all)
  • Process Chemistry and Technology
  • Computer Science Applications
  • Fluid Flow and Transfer Processes

指紋 深入研究「Surface Characteristics and Cell Adhesion Behaviors of the Anodized Biomedical Stainless Steel」主題。共同形成了獨特的指紋。