Surface analysis of titanium biological modification with glow discharge

Yu Chi Chang, Sheng Wei Feng, Haw Ming Huang, Nai Chia Teng, Che Tong Lin, Hsi Kuei Lin, Peter D. Wang, Wei Jen Chang

研究成果: 雜誌貢獻文章同行評審

11 引文 斯高帕斯(Scopus)

摘要

BACKGROUND: Glow discharge plasma (GDP) technology has been used to graft various proteins to the titanium surface, including albumin, type I collagen, but without fibronectin.

PURPOSE: The aim of this study was to evaluate and analyze the physical properties of fibronectin-grafted titanium surfaces after GDP treatment.

MATERIALS AND METHODS: Grade II titanium discs after cleaning and autoclaving were considered as original specimens, thus divided into four groups. The groups were different upon two treatments (GDP only and fibronectin grafting after GDP) and two storage temperature (4°C and 25°C). The implant surface morphology was characterized by scanning electron microscopy (SEM), roughness measurement, and wettability evaluation. The concentration relationship of fibronectin was by fluorescein isothiocyanate (FITC) labeling.

RESULTS: SEM images showed that regular planar texture revealed on the surface of GDP-treated group, and irregular-folding protein was found on the fibronectin-grafted discs. Fibronectin-grafted groups had higher hydrophilicity and greater surface roughness than GDP-treated specimens. The storage temperature did not make obvious difference on the surface topography, wettability, and roughness. The number of fibronectin dots on the titanium surface labeling by FITC had positive relationship with the concentration of fibronectin solution used.

CONCLUSIONS: Biologically modified titanium surface is more hydrophilic and rougher than GDP-treated ones. GDP treatment combined with fibronectin grafting increased the surface hydrophilicity and surface roughness of titanium discs, which may attribute to the affinity of cell adhesion, migration, proliferation, and differentiation.
原文英語
頁(從 - 到)469-475
頁數7
期刊Clinical Implant Dentistry and Related Research
17
發行號3
DOIs
出版狀態已發佈 - 六月 1 2015

ASJC Scopus subject areas

  • 口腔外科
  • 牙科 (全部)

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