Supratentorial cerebrospinal fluid production rate in healthy adults: Quantification with two-dimensional cine phase-contrast MR imaging with high temporal and spatial resolution

Teng Yi Huang, Hsiao Wen Chung, Ming Yen Chen, Lung Hui Giiang, Shy Chyi Chin, Chang Shin Lee, Cheng Yu Chen, Yi Jui Liu

研究成果: 雜誌貢獻文章同行評審

63 引文 斯高帕斯(Scopus)

摘要

A method for objectively determining supratentorial cerebrospinal fluid (CSF) production rate is described. The method employs cine phase-contrast magnetic resonance imaging with high temporal and spatial resolution at the level of the aqueduct of Sylvius. Automatic encircling of the aqueduct was accomplished by using a pulsatility-based segmentation approach. Results in 23 healthy adults (18 men, five women; age range, 21-39 years) yielded an average CSF production rate of 305 μL/min ± 145 (standard deviation); this rate is in good agreement with literature-reported values obtained with invasive ventriculolumbar perfusion measurements. Average operator imprecision was 23.1% if automatic segmentation was not used. The proposed method is potentially an effective means for measuring supratentorial CSF production rate in humans.
原文英語
頁(從 - 到)603-608
頁數6
期刊Radiology
233
發行號2
DOIs
出版狀態已發佈 - 11月 2004
對外發佈

ASJC Scopus subject areas

  • 放射與超音波技術

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