Substituent Effect on the Chlorination of 2-Alkoxypyridines to give 2-Chloropyridines under Vilsmeier-Haack Conditions

Long Li Lai, Pen Yuan Lin, Jy Shih Wang, Jih Ru Hwu, Min Jen Shiao, Shwu Chen Tsay

研究成果: 雜誌貢獻文章同行評審

5 引文 斯高帕斯(Scopus)

摘要

Various substituted 2-alkoxypyridines were converted into the corresponding 2-chloropyridines in 28-91% yields by use of POCl3 and DMF, in which the methyl, halogen, ester and nitro groups displayed an activating effect; in contrast, an amino group exhibited a deactivating effect.

原文英語
頁(從 - 到)194-195
頁數2
期刊Journal of Chemical Research - Part S
發行號4
出版狀態已發佈 - 四月 1996
對外發佈Yes

ASJC Scopus subject areas

  • Chemistry(all)

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